Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159025165> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2159025165 endingPage "3011" @default.
- W2159025165 startingPage "3005" @default.
- W2159025165 abstract "The role of phase variation of lic1A, lic2A and lic3A in the ability of Haemophilus influenzae type b to colonize the nasopharynx, bloodstream and cerebrospinal fluid (CSF) of infants was investigated. This was achieved by using PCR to determine the number of 5'-CAAT-3' repeats present in each gene, which is indicative of whether each ORF can be expressed. Multiple PCR products of different intensities were amplified from all three genes at each site sampled. This indicated that the nasopharynx, bloodstream and CSF were colonized by a heterogeneous population of organisms, expressing different combinations of lic genes. At each site however, a predominant PCR product was amplified from each gene, indicating that organisms with this genotype were the most abundant. The number of 5'-CAAT-3' repeats in this predominant product varied depending upon whether organisms were isolated from the nasopharynx, bloodstream or CSF. These observations suggest that the expression of different combinations of lic genes may influence the efficiency with which H. influenzae colonizes the nasopharynx, bloodstream and CSF of infant rats." @default.
- W2159025165 created "2016-06-24" @default.
- W2159025165 creator A5020924103 @default.
- W2159025165 creator A5049631124 @default.
- W2159025165 creator A5085180363 @default.
- W2159025165 date "1999-11-01" @default.
- W2159025165 modified "2023-10-14" @default.
- W2159025165 title "Phase variation of lic1A, lic2A and lic3A in colonization of the nasopharynx, bloodstream and cerebrospinal fluid by Haemophilus influenzae type b" @default.
- W2159025165 cites W1969506789 @default.
- W2159025165 cites W1979687902 @default.
- W2159025165 cites W1987292348 @default.
- W2159025165 cites W2016648215 @default.
- W2159025165 cites W2042493244 @default.
- W2159025165 cites W2048362340 @default.
- W2159025165 cites W2055953441 @default.
- W2159025165 cites W2084940248 @default.
- W2159025165 cites W2111788032 @default.
- W2159025165 cites W2113765753 @default.
- W2159025165 cites W2150713210 @default.
- W2159025165 cites W2153415475 @default.
- W2159025165 cites W2161007290 @default.
- W2159025165 cites W2176289110 @default.
- W2159025165 cites W2183139745 @default.
- W2159025165 doi "https://doi.org/10.1099/00221287-145-11-3005" @default.
- W2159025165 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10589708" @default.
- W2159025165 hasPublicationYear "1999" @default.
- W2159025165 type Work @default.
- W2159025165 sameAs 2159025165 @default.
- W2159025165 citedByCount "19" @default.
- W2159025165 countsByYear W21590251652013 @default.
- W2159025165 countsByYear W21590251652014 @default.
- W2159025165 countsByYear W21590251652015 @default.
- W2159025165 countsByYear W21590251652016 @default.
- W2159025165 countsByYear W21590251652018 @default.
- W2159025165 countsByYear W21590251652019 @default.
- W2159025165 countsByYear W21590251652023 @default.
- W2159025165 crossrefType "journal-article" @default.
- W2159025165 hasAuthorship W2159025165A5020924103 @default.
- W2159025165 hasAuthorship W2159025165A5049631124 @default.
- W2159025165 hasAuthorship W2159025165A5085180363 @default.
- W2159025165 hasBestOaLocation W21590251651 @default.
- W2159025165 hasConcept C104317684 @default.
- W2159025165 hasConcept C135763542 @default.
- W2159025165 hasConcept C159047783 @default.
- W2159025165 hasConcept C169760540 @default.
- W2159025165 hasConcept C179069550 @default.
- W2159025165 hasConcept C2776925733 @default.
- W2159025165 hasConcept C2779651940 @default.
- W2159025165 hasConcept C2908647359 @default.
- W2159025165 hasConcept C49105822 @default.
- W2159025165 hasConcept C501593827 @default.
- W2159025165 hasConcept C54355233 @default.
- W2159025165 hasConcept C60987743 @default.
- W2159025165 hasConcept C71924100 @default.
- W2159025165 hasConcept C86803240 @default.
- W2159025165 hasConcept C89423630 @default.
- W2159025165 hasConcept C99454951 @default.
- W2159025165 hasConceptScore W2159025165C104317684 @default.
- W2159025165 hasConceptScore W2159025165C135763542 @default.
- W2159025165 hasConceptScore W2159025165C159047783 @default.
- W2159025165 hasConceptScore W2159025165C169760540 @default.
- W2159025165 hasConceptScore W2159025165C179069550 @default.
- W2159025165 hasConceptScore W2159025165C2776925733 @default.
- W2159025165 hasConceptScore W2159025165C2779651940 @default.
- W2159025165 hasConceptScore W2159025165C2908647359 @default.
- W2159025165 hasConceptScore W2159025165C49105822 @default.
- W2159025165 hasConceptScore W2159025165C501593827 @default.
- W2159025165 hasConceptScore W2159025165C54355233 @default.
- W2159025165 hasConceptScore W2159025165C60987743 @default.
- W2159025165 hasConceptScore W2159025165C71924100 @default.
- W2159025165 hasConceptScore W2159025165C86803240 @default.
- W2159025165 hasConceptScore W2159025165C89423630 @default.
- W2159025165 hasConceptScore W2159025165C99454951 @default.
- W2159025165 hasIssue "11" @default.
- W2159025165 hasLocation W21590251651 @default.
- W2159025165 hasLocation W21590251652 @default.
- W2159025165 hasOpenAccess W2159025165 @default.
- W2159025165 hasPrimaryLocation W21590251651 @default.
- W2159025165 hasRelatedWork W122156902 @default.
- W2159025165 hasRelatedWork W1964124185 @default.
- W2159025165 hasRelatedWork W2015812039 @default.
- W2159025165 hasRelatedWork W2037317725 @default.
- W2159025165 hasRelatedWork W2081522637 @default.
- W2159025165 hasRelatedWork W2741998075 @default.
- W2159025165 hasRelatedWork W3207388809 @default.
- W2159025165 hasRelatedWork W4220976926 @default.
- W2159025165 hasRelatedWork W4253847186 @default.
- W2159025165 hasRelatedWork W4386270592 @default.
- W2159025165 hasVolume "145" @default.
- W2159025165 isParatext "false" @default.
- W2159025165 isRetracted "false" @default.
- W2159025165 magId "2159025165" @default.
- W2159025165 workType "article" @default.