Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159193344> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2159193344 endingPage "229" @default.
- W2159193344 startingPage "227" @default.
- W2159193344 abstract "Long standing errors in major pharmacopoeiae (BP,USP, and Eu.Ph.) concerning the absolute stereochemistry of the widely used antituberculosis drug (+)-ethambutol have been clarified by unambiguous synthesis and chiral HPLC. on a Pirkle, covalent D-phenylglycine column of perbenzoyl derivatives of each stereomer; the enantiomeric (−)-(R,R) and (+)-(S,S)-ethambutols together with the optically inactive (meso)-(R,S)-ethambutol. This paper describes how circular dichroism (CD) alone and combined with HPLC is used to demonstrate this chiral separation and also to confirm the absolute stereochemistry of each stereomer of ethambutol and its synthetic precursor 2-aminobutan-1-ol from studies of „exciton coupling.”︁ The strengths and weaknesses of these chiral techniques are discussed." @default.
- W2159193344 created "2016-06-24" @default.
- W2159193344 creator A5023160506 @default.
- W2159193344 creator A5060754471 @default.
- W2159193344 creator A5065052875 @default.
- W2159193344 creator A5071396961 @default.
- W2159193344 creator A5080750870 @default.
- W2159193344 date "1992-01-01" @default.
- W2159193344 modified "2023-09-24" @default.
- W2159193344 title "Chiral hplc-cd studies of the antituberculosis drug (+)-ethambutol" @default.
- W2159193344 cites W2055060316 @default.
- W2159193344 cites W2071317239 @default.
- W2159193344 doi "https://doi.org/10.1002/chir.530040405" @default.
- W2159193344 hasPublicationYear "1992" @default.
- W2159193344 type Work @default.
- W2159193344 sameAs 2159193344 @default.
- W2159193344 citedByCount "6" @default.
- W2159193344 countsByYear W21591933442020 @default.
- W2159193344 crossrefType "journal-article" @default.
- W2159193344 hasAuthorship W2159193344A5023160506 @default.
- W2159193344 hasAuthorship W2159193344A5060754471 @default.
- W2159193344 hasAuthorship W2159193344A5065052875 @default.
- W2159193344 hasAuthorship W2159193344A5071396961 @default.
- W2159193344 hasAuthorship W2159193344A5080750870 @default.
- W2159193344 hasConcept C121332964 @default.
- W2159193344 hasConcept C124668440 @default.
- W2159193344 hasConcept C133571119 @default.
- W2159193344 hasConcept C16838498 @default.
- W2159193344 hasConcept C179998833 @default.
- W2159193344 hasConcept C185592680 @default.
- W2159193344 hasConcept C20621625 @default.
- W2159193344 hasConcept C21951064 @default.
- W2159193344 hasConcept C25170562 @default.
- W2159193344 hasConcept C2775843808 @default.
- W2159193344 hasConcept C2776228421 @default.
- W2159193344 hasConcept C2778564446 @default.
- W2159193344 hasConcept C43617362 @default.
- W2159193344 hasConcept C486523 @default.
- W2159193344 hasConcept C501593827 @default.
- W2159193344 hasConcept C55493867 @default.
- W2159193344 hasConcept C62520636 @default.
- W2159193344 hasConcept C71240020 @default.
- W2159193344 hasConcept C7602139 @default.
- W2159193344 hasConceptScore W2159193344C121332964 @default.
- W2159193344 hasConceptScore W2159193344C124668440 @default.
- W2159193344 hasConceptScore W2159193344C133571119 @default.
- W2159193344 hasConceptScore W2159193344C16838498 @default.
- W2159193344 hasConceptScore W2159193344C179998833 @default.
- W2159193344 hasConceptScore W2159193344C185592680 @default.
- W2159193344 hasConceptScore W2159193344C20621625 @default.
- W2159193344 hasConceptScore W2159193344C21951064 @default.
- W2159193344 hasConceptScore W2159193344C25170562 @default.
- W2159193344 hasConceptScore W2159193344C2775843808 @default.
- W2159193344 hasConceptScore W2159193344C2776228421 @default.
- W2159193344 hasConceptScore W2159193344C2778564446 @default.
- W2159193344 hasConceptScore W2159193344C43617362 @default.
- W2159193344 hasConceptScore W2159193344C486523 @default.
- W2159193344 hasConceptScore W2159193344C501593827 @default.
- W2159193344 hasConceptScore W2159193344C55493867 @default.
- W2159193344 hasConceptScore W2159193344C62520636 @default.
- W2159193344 hasConceptScore W2159193344C71240020 @default.
- W2159193344 hasConceptScore W2159193344C7602139 @default.
- W2159193344 hasIssue "4" @default.
- W2159193344 hasLocation W21591933441 @default.
- W2159193344 hasOpenAccess W2159193344 @default.
- W2159193344 hasPrimaryLocation W21591933441 @default.
- W2159193344 hasRelatedWork W2009776446 @default.
- W2159193344 hasRelatedWork W2021792606 @default.
- W2159193344 hasRelatedWork W2048525790 @default.
- W2159193344 hasRelatedWork W2101925719 @default.
- W2159193344 hasRelatedWork W2315647372 @default.
- W2159193344 hasRelatedWork W2401616610 @default.
- W2159193344 hasRelatedWork W2570757224 @default.
- W2159193344 hasRelatedWork W2971362600 @default.
- W2159193344 hasRelatedWork W4240765782 @default.
- W2159193344 hasRelatedWork W2082336286 @default.
- W2159193344 hasVolume "4" @default.
- W2159193344 isParatext "false" @default.
- W2159193344 isRetracted "false" @default.
- W2159193344 magId "2159193344" @default.
- W2159193344 workType "article" @default.