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• W2159262288 abstract "Objectives: Drugs used in dental practice have often a large therapeutic index, are usually in a single dose or in short-term form and frequently used for elective procedures, however, drug-drug interactions (DDI) with prescribed medication, as well as with dietary supplements (DS) or herbal remedies (HR) may occur. Nevertheless, pharmacoepidemiologic data in this field are scarce. The aim of the present study was to investigate the risk of DDI in dentistry patients investigating use pattern of drugs and DS/HR. Methods: Dentistry outpatients were consecutively enrolled and surveyed through a semistructured questionnaires divided into three sections in order to collect sociodemographical, pharmacological, DS and HR data. Potential risk of interactions was evaluated checking any potential interaction reported in literature between the drugs, DS and HR used in the studied population and treatments commonly used in dentistry practice. Results: 100 patients were enrolled, 37% were under prescribed medications, mainly represented by cardiovascular drugs. 82 potential DDI were detected and were principally represented by potential interactions with NSAIDs (88%) and antimicrobials (75%). Conclusions: The study underlines that dentistry outpatients are often under a pharmacological tretament and polypharmacy is not unfrequent, with a high risk of DDI with treatment prescribed by the dentist. Therefore, a careful evaluation of all the medications including DS and HR and a the knowledge of potential interactions with dentistry treatments is mandatory to avoid the risk of DDI." @default.
• W2159262288 created "2016-06-24" @default.
• W2159262288 creator A5003659147 @default.
• W2159262288 date "2013-01-01" @default.
• W2159262288 modified "2023-09-26" @default.
• W2159262288 title "ALL MEDICINES ARE DRUGS BUT NOT ALL DRUGS ARE MEDICINES: PHARMACOEPIDEMIOLOGICAL APPROACHES TO ASSESS THE USE OF PRESCRIPTION/OTC MEDICINES, HERBS, DIETARY SUPPLEMENTS AND ILLICIT DRUGS" @default.
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