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• W2159306050 startingPage "1829" @default.
• W2159306050 abstract "In the present study, investigations were carried out to screen the anticancer activities of fenugreek seed oil against cancer cell lines (HEp-2, MCF-7, WISH cells), and a normal cell line (Vero cells). Cytotoxicity was assessed with MTT and NRU assays, and cellular morphological alterations were studied using phase contrast light microscopy. All cells were exposed toi 10-1000 μg/ml of fenugreek seed oil for 24 h. The results show that fenugreek seed oil significantly reduced the cell viability, and altered the cellular morphology in a dose dependent manner. Among the cell lines, HEp-2 cells showed the highest decrease in cell viability, followed by MCF-7, WISH, and Vero cells by MTT and NRU assays. Cell viability at 1000 μg/ml was recorded as 55% in HEp-2 cells, 67% in MCF-7 cells, 75% in WISH cells, and 86% in Vero cells. The present study provides preliminary screening data for fenugreek seed oil pointing to potent cytotoxicity against cancer cells." @default.
• W2159306050 created "2016-06-24" @default.
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• W2159306050 date "2013-03-30" @default.
• W2159306050 modified "2023-10-10" @default.
• W2159306050 title "In Vitro Cytotoxic Activity of Seed Oil of Fenugreek Against Various Cancer Cell Lines" @default.
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• W2159306050 doi "https://doi.org/10.7314/apjcp.2013.14.3.1829" @default.
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