Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159394959> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2159394959 abstract "Artemisinin and its derivatives are very important new class of antimalarial drugs. One of the most important artemisinin derivatives is artemether. The antiparasitic activity of artemether as a derivative of artemisinin is related to endoperoxide bridge in its structure. The aim of this study was the evaluation of antileishmanial effect of artemether, with more focus on its apoptotic effect. In this study we used artemether in concentration of 5, 10, 25, 50 and 100 μg/mL for promastigote assay, promastigote proliferation measurements by MTT assay, detection of apoptotic cells by Flow cytometry analysis and DNA ladder assay. The application of artemether, promastigote IC50 was measured as 25 μg/mL. The percentage of apoptotic promastigotes by using 25 μg/mL of artemether was 42.28. The results of present study showed that artemether has inhibition effect on intracellular and extracellular growth of Leishmania major. Promastigotes of Leishmania major undergo apoptosis after exposure to artemether." @default.
- W2159394959 created "2016-06-24" @default.
- W2159394959 creator A5001698060 @default.
- W2159394959 creator A5006720918 @default.
- W2159394959 creator A5044638394 @default.
- W2159394959 date "2013-01-01" @default.
- W2159394959 modified "2023-09-29" @default.
- W2159394959 title "In-vitro Evaluation of Antileishmanial Activity and Toxicity of Artemether with Focus on its Apoptotic Effect." @default.
- W2159394959 cites W1882065322 @default.
- W2159394959 cites W1916662323 @default.
- W2159394959 cites W1951642591 @default.
- W2159394959 cites W1963767998 @default.
- W2159394959 cites W1964008976 @default.
- W2159394959 cites W1971491292 @default.
- W2159394959 cites W1981182114 @default.
- W2159394959 cites W1991072114 @default.
- W2159394959 cites W2027956620 @default.
- W2159394959 cites W2037063107 @default.
- W2159394959 cites W2054743571 @default.
- W2159394959 cites W2063597830 @default.
- W2159394959 cites W2083068805 @default.
- W2159394959 cites W2085398533 @default.
- W2159394959 cites W2089288068 @default.
- W2159394959 cites W2100518513 @default.
- W2159394959 cites W2106005860 @default.
- W2159394959 cites W2115973389 @default.
- W2159394959 cites W2141276562 @default.
- W2159394959 cites W2142025416 @default.
- W2159394959 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3920718" @default.
- W2159394959 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24523770" @default.
- W2159394959 hasPublicationYear "2013" @default.
- W2159394959 type Work @default.
- W2159394959 sameAs 2159394959 @default.
- W2159394959 citedByCount "12" @default.
- W2159394959 countsByYear W21593949592014 @default.
- W2159394959 countsByYear W21593949592015 @default.
- W2159394959 countsByYear W21593949592017 @default.
- W2159394959 countsByYear W21593949592018 @default.
- W2159394959 countsByYear W21593949592019 @default.
- W2159394959 countsByYear W21593949592020 @default.
- W2159394959 countsByYear W21593949592021 @default.
- W2159394959 countsByYear W21593949592023 @default.
- W2159394959 crossrefType "journal-article" @default.
- W2159394959 hasAuthorship W2159394959A5001698060 @default.
- W2159394959 hasAuthorship W2159394959A5006720918 @default.
- W2159394959 hasAuthorship W2159394959A5044638394 @default.
- W2159394959 hasConcept C178790620 @default.
- W2159394959 hasConcept C185592680 @default.
- W2159394959 hasConcept C190283241 @default.
- W2159394959 hasConcept C202751555 @default.
- W2159394959 hasConcept C203014093 @default.
- W2159394959 hasConcept C2776120307 @default.
- W2159394959 hasConcept C2778048844 @default.
- W2159394959 hasConcept C2778118209 @default.
- W2159394959 hasConcept C2778371730 @default.
- W2159394959 hasConcept C2779691961 @default.
- W2159394959 hasConcept C2780783641 @default.
- W2159394959 hasConcept C29730261 @default.
- W2159394959 hasConcept C55493867 @default.
- W2159394959 hasConcept C556039675 @default.
- W2159394959 hasConcept C71924100 @default.
- W2159394959 hasConcept C86803240 @default.
- W2159394959 hasConcept C98274493 @default.
- W2159394959 hasConceptScore W2159394959C178790620 @default.
- W2159394959 hasConceptScore W2159394959C185592680 @default.
- W2159394959 hasConceptScore W2159394959C190283241 @default.
- W2159394959 hasConceptScore W2159394959C202751555 @default.
- W2159394959 hasConceptScore W2159394959C203014093 @default.
- W2159394959 hasConceptScore W2159394959C2776120307 @default.
- W2159394959 hasConceptScore W2159394959C2778048844 @default.
- W2159394959 hasConceptScore W2159394959C2778118209 @default.
- W2159394959 hasConceptScore W2159394959C2778371730 @default.
- W2159394959 hasConceptScore W2159394959C2779691961 @default.
- W2159394959 hasConceptScore W2159394959C2780783641 @default.
- W2159394959 hasConceptScore W2159394959C29730261 @default.
- W2159394959 hasConceptScore W2159394959C55493867 @default.
- W2159394959 hasConceptScore W2159394959C556039675 @default.
- W2159394959 hasConceptScore W2159394959C71924100 @default.
- W2159394959 hasConceptScore W2159394959C86803240 @default.
- W2159394959 hasConceptScore W2159394959C98274493 @default.
- W2159394959 hasLocation W21593949591 @default.
- W2159394959 hasOpenAccess W2159394959 @default.
- W2159394959 hasPrimaryLocation W21593949591 @default.
- W2159394959 hasRelatedWork W2086152299 @default.
- W2159394959 hasRelatedWork W2092625404 @default.
- W2159394959 hasRelatedWork W2107915297 @default.
- W2159394959 hasRelatedWork W2148485023 @default.
- W2159394959 hasRelatedWork W2167634412 @default.
- W2159394959 hasRelatedWork W2367720516 @default.
- W2159394959 hasRelatedWork W2495128365 @default.
- W2159394959 hasRelatedWork W592946618 @default.
- W2159394959 hasRelatedWork W646702389 @default.
- W2159394959 isParatext "false" @default.
- W2159394959 isRetracted "false" @default.
- W2159394959 magId "2159394959" @default.
- W2159394959 workType "article" @default.