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• W2159483735 startingPage "i71" @default.
• W2159483735 abstract "Massive haemorrhage requires massive transfusion (MT) to maintain adequate circulation and haemostasis. For optimal management of massively bleeding patients, regardless of aetiology (trauma, obstetrical, surgical), effective preparation and communication between transfusion and other laboratory services and clinical teams are essential. A well-defined MT protocol is a valuable tool to delineate how blood products are ordered, prepared, and delivered; determine laboratory algorithms to use as transfusion guidelines; and outline duties and facilitate communication between involved personnel. In MT patients, it is crucial to practice damage control resuscitation and to administer blood products early in the resuscitation. Trauma patients are often admitted with early trauma-induced coagulopathy (ETIC), which is associated with mortality; the aetiology of ETIC is likely multifactorial. Current data support that trauma patients treated with higher ratios of plasma and platelet to red blood cell transfusions have improved outcomes, but further clinical investigation is needed. Additionally, tranexamic acid has been shown to decrease the mortality in trauma patients requiring MT. Greater use of cryoprecipitate or fibrinogen concentrate might be beneficial in MT patients from obstetrical causes. The risks and benefits for other therapies (prothrombin complex concentrate, recombinant activated factor VII, or whole blood) are not clearly defined in MT patients. Throughout the resuscitation, the patient should be closely monitored and both metabolic and coagulation abnormalities corrected. Further studies are needed to clarify the optimal ratios of blood products, treatment based on underlying clinical disorder, use of alternative therapies, and integration of laboratory testing results in the management of massively bleeding patients." @default.
• W2159483735 created "2016-06-24" @default.
• W2159483735 creator A5026917289 @default.
• W2159483735 creator A5077643811 @default.
• W2159483735 date "2013-12-01" @default.
• W2159483735 modified "2023-10-14" @default.
• W2159483735 title "Update on massive transfusion" @default.
• W2159483735 cites W1523698303 @default.
• W2159483735 cites W1572873255 @default.
• W2159483735 cites W1605629353 @default.
• W2159483735 cites W1759594931 @default.
• W2159483735 cites W1898221764 @default.
• W2159483735 cites W1939149497 @default.
• W2159483735 cites W1945750826 @default.
• W2159483735 cites W1956566465 @default.
• W2159483735 cites W1966383370 @default.
• W2159483735 cites W1967433109 @default.
• W2159483735 cites W1971358936 @default.
• W2159483735 cites W1979769460 @default.
• W2159483735 cites W1980149090 @default.
• W2159483735 cites W1981116862 @default.
• W2159483735 cites W1992034786 @default.
• W2159483735 cites W1993994572 @default.
• W2159483735 cites W1994720669 @default.
• W2159483735 cites W1995955953 @default.
• W2159483735 cites W1996709257 @default.
• W2159483735 cites W2003993899 @default.
• W2159483735 cites W2010277284 @default.
• W2159483735 cites W2010930419 @default.
• W2159483735 cites W2011356417 @default.
• W2159483735 cites W2011749594 @default.
• W2159483735 cites W2015667316 @default.
• W2159483735 cites W2015958583 @default.
• W2159483735 cites W2017755230 @default.
• W2159483735 cites W2020706581 @default.
• W2159483735 cites W2029690372 @default.
• W2159483735 cites W2031433694 @default.
• W2159483735 cites W2033733394 @default.
• W2159483735 cites W2035934312 @default.
• W2159483735 cites W2036481028 @default.
• W2159483735 cites W2038130486 @default.
• W2159483735 cites W2038232554 @default.
• W2159483735 cites W2040037221 @default.
• W2159483735 cites W2040767898 @default.
• W2159483735 cites W2042481170 @default.
• W2159483735 cites W2046550253 @default.
• W2159483735 cites W2050653657 @default.
• W2159483735 cites W2054111408 @default.
• W2159483735 cites W2057251172 @default.
• W2159483735 cites W2057902900 @default.
• W2159483735 cites W2059069035 @default.
• W2159483735 cites W2061152996 @default.
• W2159483735 cites W2070371518 @default.
• W2159483735 cites W2080347790 @default.
• W2159483735 cites W2080870870 @default.
• W2159483735 cites W2085024400 @default.
• W2159483735 cites W2085143218 @default.
• W2159483735 cites W2088856790 @default.
• W2159483735 cites W2091685079 @default.
• W2159483735 cites W2096792421 @default.
• W2159483735 cites W2099138598 @default.
• W2159483735 cites W2100099564 @default.
• W2159483735 cites W2101494433 @default.
• W2159483735 cites W2102919367 @default.
• W2159483735 cites W2103297882 @default.
• W2159483735 cites W2103935614 @default.
• W2159483735 cites W2108626978 @default.
• W2159483735 cites W2110820970 @default.
• W2159483735 cites W2111292680 @default.
• W2159483735 cites W2111548427 @default.
• W2159483735 cites W2116386817 @default.
• W2159483735 cites W2121864664 @default.
• W2159483735 cites W2124943657 @default.
• W2159483735 cites W2126420535 @default.
• W2159483735 cites W2135878370 @default.
• W2159483735 cites W2136293082 @default.
• W2159483735 cites W2136753338 @default.
• W2159483735 cites W2137581071 @default.
• W2159483735 cites W2140681770 @default.
• W2159483735 cites W2143986922 @default.
• W2159483735 cites W2150468788 @default.
• W2159483735 cites W2153717258 @default.
• W2159483735 cites W2161206101 @default.
• W2159483735 cites W2162249417 @default.
• W2159483735 cites W2164932233 @default.
• W2159483735 cites W2165755420 @default.
• W2159483735 cites W2167136042 @default.
• W2159483735 cites W2342997386 @default.
• W2159483735 cites W2355654874 @default.
• W2159483735 cites W4246625307 @default.
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• W2159483735 doi "https://doi.org/10.1093/bja/aet376" @default.
• W2159483735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24335401" @default.
• W2159483735 hasPublicationYear "2013" @default.
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