Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159498587> ?p ?o ?g. }
- W2159498587 endingPage "3154" @default.
- W2159498587 startingPage "3146" @default.
- W2159498587 abstract "Nerve fibers of the C57BL/6/Ola mouse exhibit very slow Wallerian degeneration following axotomy, thus allowing prolonged observation of mammalian axons separated from their cell bodies. The present study utilized teased-fiber preparations, silver histochemistry, immunocytochemistry, and electron microscopy to examine the distribution of axonal components in the distal stumps of axotomized sciatic nerves in C57BL/6/Ola mice. In examining nerve segments at varying intervals after nerve transection, we found no evidence of proximal-to-distal “emptying out” of the cytoskeleton, as would be predicted if the cytoskeleton in these transected nerves were undergoing anterograde transport as an assembled structure. Instead, we observed a gradual redistribution of cytoskeletal constituents over time, dominated by the progressive accumulation of neurofilaments at the severed ends of axons. In particular, there were massive accumulations at the proximal ends of the distal stumps. These results strongly suggest that, at least in transected nerve fibers, neurofilaments can be transported bidirectionally." @default.
- W2159498587 created "2016-06-24" @default.
- W2159498587 creator A5008654001 @default.
- W2159498587 creator A5070384343 @default.
- W2159498587 date "1991-10-01" @default.
- W2159498587 modified "2023-10-18" @default.
- W2159498587 title "Neurofilament redistribution in transected nerves: evidence for bidirectional transport of neurofilaments" @default.
- W2159498587 cites W1548296683 @default.
- W2159498587 cites W1576914486 @default.
- W2159498587 cites W1654314171 @default.
- W2159498587 cites W1841103857 @default.
- W2159498587 cites W1964748039 @default.
- W2159498587 cites W1972249490 @default.
- W2159498587 cites W1977054468 @default.
- W2159498587 cites W1982032761 @default.
- W2159498587 cites W1984218330 @default.
- W2159498587 cites W1992888811 @default.
- W2159498587 cites W1998832444 @default.
- W2159498587 cites W2004012808 @default.
- W2159498587 cites W2011763423 @default.
- W2159498587 cites W2028731254 @default.
- W2159498587 cites W2031567153 @default.
- W2159498587 cites W2036095715 @default.
- W2159498587 cites W2038231740 @default.
- W2159498587 cites W2041549715 @default.
- W2159498587 cites W2043095101 @default.
- W2159498587 cites W2045880711 @default.
- W2159498587 cites W2054115855 @default.
- W2159498587 cites W2057914712 @default.
- W2159498587 cites W2060863809 @default.
- W2159498587 cites W2065042412 @default.
- W2159498587 cites W2065495285 @default.
- W2159498587 cites W2066711877 @default.
- W2159498587 cites W2073531559 @default.
- W2159498587 cites W2075387470 @default.
- W2159498587 cites W2086202990 @default.
- W2159498587 cites W2087277002 @default.
- W2159498587 cites W2090941183 @default.
- W2159498587 cites W2092433966 @default.
- W2159498587 cites W2094584212 @default.
- W2159498587 cites W2106279306 @default.
- W2159498587 cites W2125659223 @default.
- W2159498587 cites W2146014141 @default.
- W2159498587 cites W2153155642 @default.
- W2159498587 cites W21600353 @default.
- W2159498587 cites W2166461802 @default.
- W2159498587 cites W2423486792 @default.
- W2159498587 doi "https://doi.org/10.1523/jneurosci.11-10-03146.1991" @default.
- W2159498587 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6575450" @default.
- W2159498587 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1941078" @default.
- W2159498587 hasPublicationYear "1991" @default.
- W2159498587 type Work @default.
- W2159498587 sameAs 2159498587 @default.
- W2159498587 citedByCount "60" @default.
- W2159498587 countsByYear W21594985872012 @default.
- W2159498587 countsByYear W21594985872013 @default.
- W2159498587 countsByYear W21594985872018 @default.
- W2159498587 countsByYear W21594985872021 @default.
- W2159498587 countsByYear W21594985872022 @default.
- W2159498587 countsByYear W21594985872023 @default.
- W2159498587 crossrefType "journal-article" @default.
- W2159498587 hasAuthorship W2159498587A5008654001 @default.
- W2159498587 hasAuthorship W2159498587A5070384343 @default.
- W2159498587 hasBestOaLocation W21594985871 @default.
- W2159498587 hasConcept C105702510 @default.
- W2159498587 hasConcept C120665830 @default.
- W2159498587 hasConcept C121332964 @default.
- W2159498587 hasConcept C134018914 @default.
- W2159498587 hasConcept C142669718 @default.
- W2159498587 hasConcept C1491633281 @default.
- W2159498587 hasConcept C157207234 @default.
- W2159498587 hasConcept C169760540 @default.
- W2159498587 hasConcept C185592680 @default.
- W2159498587 hasConcept C203014093 @default.
- W2159498587 hasConcept C204232928 @default.
- W2159498587 hasConcept C2779530196 @default.
- W2159498587 hasConcept C2779683492 @default.
- W2159498587 hasConcept C2780862704 @default.
- W2159498587 hasConcept C2781149210 @default.
- W2159498587 hasConcept C35866371 @default.
- W2159498587 hasConcept C37753355 @default.
- W2159498587 hasConcept C529278444 @default.
- W2159498587 hasConcept C54355233 @default.
- W2159498587 hasConcept C70192387 @default.
- W2159498587 hasConcept C74864618 @default.
- W2159498587 hasConcept C86803240 @default.
- W2159498587 hasConcept C93877712 @default.
- W2159498587 hasConceptScore W2159498587C105702510 @default.
- W2159498587 hasConceptScore W2159498587C120665830 @default.
- W2159498587 hasConceptScore W2159498587C121332964 @default.
- W2159498587 hasConceptScore W2159498587C134018914 @default.
- W2159498587 hasConceptScore W2159498587C142669718 @default.
- W2159498587 hasConceptScore W2159498587C1491633281 @default.
- W2159498587 hasConceptScore W2159498587C157207234 @default.
- W2159498587 hasConceptScore W2159498587C169760540 @default.
- W2159498587 hasConceptScore W2159498587C185592680 @default.
- W2159498587 hasConceptScore W2159498587C203014093 @default.
- W2159498587 hasConceptScore W2159498587C204232928 @default.