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- W2159540384 abstract "Membranes made of dimyristoylphosphatidylcholine and cholesterol, one of the simplest paradigms for the study of liquid ordered-disordered phase separation, were investigated using a pulse-EPR spin-labeling method in which bimolecular collision of molecular oxygen with the nitroxide spin label is measured. This method allowed discrimination of liquid-ordered, liquid-disordered, and solid-ordered domains because the collision rates (OTP) differ in these domains. Furthermore, the oxygen transport parameter (OTP) profile across the bilayer provides unique information about the three-dimensional dynamic organization of the membrane domains. First, the OTP in the bilayer center in the liquid-ordered domain was comparable to that in the liquid-disordered domain without cholesterol, but the OTP near the membrane surface (up to carbon 9) was substantially smaller in the ordered domain, i.e., the cholesterol-based liquid-ordered domain is ordered only near the membrane surface, still retaining high levels of disorder in the bilayer center. This property may facilitate lateral mobility in ordered domains. Second, in the liquid-disordered domain, the domains with approximately 5 mol % cholesterol exhibited higher OTP than those without cholesterol, everywhere across the membrane. Third, the transmembrane OTP profile in the liquid-ordered domain that contained 50 mol % cholesterol dramatically differed from that which contained 27 mol % cholesterol." @default.
- W2159540384 created "2016-06-24" @default.
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- W2159540384 creator A5049329404 @default.
- W2159540384 creator A5057636949 @default.
- W2159540384 creator A5078050165 @default.
- W2159540384 date "2007-03-01" @default.
- W2159540384 modified "2023-10-12" @default.
- W2159540384 title "Three-Dimensional Dynamic Structure of the Liquid-Ordered Domain in Lipid Membranes as Examined by Pulse-EPR Oxygen Probing" @default.
- W2159540384 cites W1524456024 @default.
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- W2159540384 cites W1564861448 @default.
- W2159540384 cites W1570727417 @default.
- W2159540384 cites W1583154040 @default.
- W2159540384 cites W1967816643 @default.
- W2159540384 cites W1967969169 @default.
- W2159540384 cites W1968709371 @default.
- W2159540384 cites W1971607482 @default.
- W2159540384 cites W1977004640 @default.
- W2159540384 cites W1977471961 @default.
- W2159540384 cites W1978670468 @default.
- W2159540384 cites W1985868705 @default.
- W2159540384 cites W1986466164 @default.
- W2159540384 cites W1989077775 @default.
- W2159540384 cites W1993180174 @default.
- W2159540384 cites W1993400775 @default.
- W2159540384 cites W1996438987 @default.
- W2159540384 cites W1997066001 @default.
- W2159540384 cites W2000090711 @default.
- W2159540384 cites W2005379830 @default.
- W2159540384 cites W2017139834 @default.
- W2159540384 cites W2025646685 @default.
- W2159540384 cites W2026928837 @default.
- W2159540384 cites W2030487072 @default.
- W2159540384 cites W2033231167 @default.
- W2159540384 cites W2035098726 @default.
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- W2159540384 cites W2062313524 @default.
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- W2159540384 cites W2069712112 @default.
- W2159540384 cites W2070315887 @default.
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- W2159540384 cites W2072033208 @default.
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- W2159540384 cites W2086303498 @default.
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- W2159540384 cites W2105956122 @default.
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- W2159540384 cites W2131841240 @default.
- W2159540384 cites W2133593241 @default.
- W2159540384 cites W2134723427 @default.
- W2159540384 cites W2135594608 @default.
- W2159540384 cites W2135966071 @default.
- W2159540384 cites W2136795628 @default.
- W2159540384 cites W2139093579 @default.
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- W2159540384 cites W2143466814 @default.
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- W2159540384 doi "https://doi.org/10.1529/biophysj.106.097568" @default.
- W2159540384 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1796815" @default.
- W2159540384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17142270" @default.
- W2159540384 hasPublicationYear "2007" @default.
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