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- W2159548690 abstract "Acylation-stimulating protein (ASP) is an adipocyte-derived protein that contributes to fatty acid clearance. Regular exercise training improves fatty acid handling. To examine the effect of acute exercise and short-term endurance training on ASP levels. Eight untrained men (age: 23.5±3.4 y; maximal power output (Wmax): 3.7±0.6 W/kg body weight). Subjects were trained for 2 weeks. Before and after training, blood was sampled during a 3-h exercise test, and insulin sensitivity was assessed by an insulin tolerance test. Before training, ASP levels decreased during exercise (from 17.9±2.9 to 15.5±3.7 nmol/l at t=0 vs 180, P<0.05). Endurance training decreased fasting ASP levels significantly (17.9±2.9 vs 13.4±2.3 nmol/l pre- and post-training, P<0.001). Interestingly, after 2 weeks of endurance training, ASP levels tended to increase during exercise (from 13.4±2.3 to 17.2±4.5 nmol/l at t=0 vs 180, P=0.09). Baseline ASP levels correlated negatively with insulin sensitivity both before (r=−0.86, P<0.01) and after training (r=−0.82, P<0.05). Short-term endurance training reduces baseline ASP levels. These data fit with the hypothesis that reduced ASP levels indicate improved ASP sensitivity." @default.
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- W2159548690 date "2005-04-05" @default.
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- W2159548690 title "Acylation-stimulating protein: effect of acute exercise and endurance training" @default.
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- W2159548690 doi "https://doi.org/10.1038/sj.ijo.0802949" @default.
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