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- W2159580351 abstract "Chronic active Epstein-Barr virus infection (CAEBV) is a high-mortality and high-morbidity disease. To clarify the prognostic factors, a national survey was performed in Japan, and data for 82 patients who met the criteria for CAEBV were analyzed. Of these 82 patients, 47 were alive and 35 had already died. Multivariate analysis revealed that thromobocytopenia and age at disease onset were correlated with mortality. The probability of 5-year survival was 0.45 for older patients (onset age, ⩾8 years), 0.94 for younger patients (P<.001), 0.38 for patients with thrombocytopenia (platelet count <12×10 4 platelets/μL at diagnosis), and 0.76 for patients without thrombocytopenia (P=.01). Furthermore, patients with T cell infection by EBV had shorter survival times than patients with natural killer cell infection (probability of 5-year survival, 0.59 vs. 0.87; P<.009). Patients with CAEBV with late onset of disease, thrombocytopenia, and T cell infection had significantly poorer outcomes" @default.
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- W2159580351 date "2003-02-15" @default.
- W2159580351 modified "2023-10-11" @default.
- W2159580351 title "Prognostic Factors for Chronic Active Epstein‐Barr Virus Infection" @default.
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- W2159580351 doi "https://doi.org/10.1086/367988" @default.
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