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• W2159590190 abstract "Increasingly, epidemiologic and clinical data support the hypothesis that perturbations in the gastrointestinal (GI) microbiota because of antibiotic use and dietary differences in 'industrialized' countries have disrupted the normal microbiota-mediated mechanisms of immunological tolerance in the mucosa, leading to an increase in the incidence of allergic airway disease. The data supporting this 'microflora hypothesis' includes correlations between allergic airway disease and (1) antibiotic use early in life, (2) altered fecal microbiota and (3) dietary changes over the past two decades. Our laboratory has recently demonstrated that mice can develop allergic airway responses to allergens if their endogenous microbiota is altered at the time of first allergen exposure. These experimental and clinical observations are consistent with other studies demonstrating that the endogenous microbiota plays a significant role in shaping the development of the immune system. Data are beginning to accumulate that a 'balanced' microbiota plays a positive role in maintaining mucosal immunologic tolerance long after post-natal development. Other studies have demonstrated that even small volumes delivered to the nasopharynx largely end up in the GI tract, suggesting that airway tolerance and oral tolerance may operate simultaneously. The mechanism of microbiota modulation of host immunity is not known; however, host and microbial oxylipins are one potential set of immunomodulatory molecules that may control mucosal tolerance. The cumulative data are beginning to support the notion that probiotic and prebiotic strategies be considered for patients coming off of antibiotic therapy." @default.
• W2159590190 created "2016-06-24" @default.
• W2159590190 creator A5032940071 @default.
• W2159590190 creator A5083690478 @default.
• W2159590190 date "2005-12-01" @default.
• W2159590190 modified "2023-10-17" @default.
• W2159590190 title "The 'microflora hypothesis' of allergic diseases" @default.
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• W2159590190 cites W1504136545 @default.
• W2159590190 cites W1524217669 @default.
• W2159590190 cites W1556548724 @default.
• W2159590190 cites W1762779731 @default.
• W2159590190 cites W1776282777 @default.
• W2159590190 cites W1965521901 @default.
• W2159590190 cites W1965895403 @default.
• W2159590190 cites W1966393653 @default.
• W2159590190 cites W1966919146 @default.
• W2159590190 cites W1968679173 @default.
• W2159590190 cites W1973597235 @default.
• W2159590190 cites W1977514490 @default.
• W2159590190 cites W1978569571 @default.
• W2159590190 cites W1979516181 @default.
• W2159590190 cites W1979732264 @default.
• W2159590190 cites W1980673401 @default.
• W2159590190 cites W1983972858 @default.
• W2159590190 cites W1986816587 @default.
• W2159590190 cites W1987571936 @default.
• W2159590190 cites W1988066089 @default.
• W2159590190 cites W1992153121 @default.
• W2159590190 cites W2000452395 @default.
• W2159590190 cites W2010410878 @default.
• W2159590190 cites W2010486136 @default.
• W2159590190 cites W2018826444 @default.
• W2159590190 cites W2022456404 @default.
• W2159590190 cites W2025192174 @default.
• W2159590190 cites W2029604938 @default.
• W2159590190 cites W2030350827 @default.
• W2159590190 cites W2032194238 @default.
• W2159590190 cites W2033859617 @default.
• W2159590190 cites W2034141629 @default.
• W2159590190 cites W2034644852 @default.
• W2159590190 cites W2035831689 @default.
• W2159590190 cites W2035912978 @default.
• W2159590190 cites W2038622845 @default.
• W2159590190 cites W2040083365 @default.
• W2159590190 cites W2041159500 @default.
• W2159590190 cites W2044534993 @default.
• W2159590190 cites W2048938643 @default.
• W2159590190 cites W2055356842 @default.
• W2159590190 cites W2055572764 @default.
• W2159590190 cites W2071544277 @default.
• W2159590190 cites W2073636322 @default.
• W2159590190 cites W2074750435 @default.
• W2159590190 cites W2080410070 @default.
• W2159590190 cites W2082874978 @default.
• W2159590190 cites W2087514028 @default.
• W2159590190 cites W2097884283 @default.
• W2159590190 cites W2100446366 @default.
• W2159590190 cites W2101083432 @default.
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• W2159590190 cites W2110924099 @default.
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• W2159590190 cites W2129021545 @default.
• W2159590190 cites W2131908875 @default.
• W2159590190 cites W2137109050 @default.
• W2159590190 cites W2138694475 @default.
• W2159590190 cites W2138961639 @default.
• W2159590190 cites W2139188807 @default.
• W2159590190 cites W2143098849 @default.
• W2159590190 cites W2146624345 @default.
• W2159590190 cites W2149488786 @default.
• W2159590190 cites W2154719091 @default.
• W2159590190 cites W2155525029 @default.
• W2159590190 cites W2155841056 @default.
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• W2159590190 cites W2159676408 @default.
• W2159590190 cites W2165528446 @default.
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• W2159590190 doi "https://doi.org/10.1111/j.1365-2222.2005.02379.x" @default.
• W2159590190 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16393316" @default.
• W2159590190 hasPublicationYear "2005" @default.
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