FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159662746> ?p ?o ?g. }

• W2159662746 endingPage "533" @default.
• W2159662746 startingPage "525" @default.
• W2159662746 abstract "Objective Alarming increases in hypertension and type 2 diabetes among Africans accentuate the need to identify factors that could serve as targets for prevention or treatment. In Caucasian populations, asymmetric dimethylarginine (ADMA), the predominant endogenous nitric oxide synthase inhibitor, is associated with cardiovascular disease and insulin resistance (IR). ADMA's counterpart, symmetric dimethylarginine (SDMA), originally thought to be inert, was recently also linked with cardiovascular risk. Since little information regarding ADMA or SDMA is available for Africans, our aim was to explore the relationships of ADMA and SDMA with measures of arterial stiffness and IR in Africans and Caucasians from South Africa. Methods The study consisted of 235 nonsmoking, nondiabetic, nonobese, human immunodeficiency virus-uninfected Africans ( n =64) and Caucasians ( n =171), aged 20–70 years. We measured blood pressure, pulse wave velocity, ADMA, SDMA, and IR (homeostasis model assessment, HOMA). Results African and Caucasian men had similar ADMA and SDMA, whereas Caucasian women had higher ADMA and SDMA than African women ( P <0.05). African men and Caucasian women indicated strong correlations of ADMA with arterial stiffness ( r =0.47, P =0.021; r =0.26, P =0.008), confirmed in multivariate analyses. Caucasian participants showed negative associations between SDMA and HOMA, being strongest in the men ( r =−0.41; P =0.002). Conclusion Our results indicate that ADMA is independently associated with vascular dysfunction in African men and Caucasian women. A strong, independent negative association of SDMA with IR was found only in Caucasian participants. The molecular explanation for this is unclear, but these findings motivate experimental studies that could shed more light on these relationships." @default.
• W2159662746 created "2016-06-24" @default.
• W2159662746 creator A5002982938 @default.
• W2159662746 creator A5017366317 @default.
• W2159662746 creator A5022132006 @default.
• W2159662746 creator A5038106053 @default.
• W2159662746 creator A5051664627 @default.
• W2159662746 creator A5057729977 @default.
• W2159662746 creator A5057764662 @default.
• W2159662746 creator A5058562840 @default.
• W2159662746 creator A5077466609 @default.
• W2159662746 creator A5079491393 @default.
• W2159662746 creator A5084405906 @default.
• W2159662746 date "2010-03-01" @default.
• W2159662746 modified "2023-10-18" @default.
• W2159662746 title "Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians" @default.
• W2159662746 cites W1531112996 @default.
• W2159662746 cites W1550111394 @default.
• W2159662746 cites W1963813104 @default.
• W2159662746 cites W1966584140 @default.
• W2159662746 cites W1973972131 @default.
• W2159662746 cites W1977480665 @default.
• W2159662746 cites W1981268963 @default.
• W2159662746 cites W1989656393 @default.
• W2159662746 cites W2001034852 @default.
• W2159662746 cites W2001038193 @default.
• W2159662746 cites W2008201148 @default.
• W2159662746 cites W2010359331 @default.
• W2159662746 cites W2019891762 @default.
• W2159662746 cites W2033029635 @default.
• W2159662746 cites W2045605650 @default.
• W2159662746 cites W2049518354 @default.
• W2159662746 cites W2061695153 @default.
• W2159662746 cites W2071172182 @default.
• W2159662746 cites W2079338983 @default.
• W2159662746 cites W2084280040 @default.
• W2159662746 cites W2088632030 @default.
• W2159662746 cites W2096042415 @default.
• W2159662746 cites W2106422918 @default.
• W2159662746 cites W2122065321 @default.
• W2159662746 cites W2123178954 @default.
• W2159662746 cites W2124620553 @default.
• W2159662746 cites W2130029726 @default.
• W2159662746 cites W2131611586 @default.
• W2159662746 cites W2136960413 @default.
• W2159662746 cites W2154655779 @default.
• W2159662746 cites W2158093977 @default.
• W2159662746 cites W2158454106 @default.
• W2159662746 cites W2165836510 @default.
• W2159662746 cites W2166415651 @default.
• W2159662746 cites W2169890089 @default.
• W2159662746 cites W2328079118 @default.
• W2159662746 cites W2099946852 @default.
• W2159662746 doi "https://doi.org/10.1530/eje-09-0865" @default.
• W2159662746 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19996198" @default.
• W2159662746 hasPublicationYear "2010" @default.
• W2159662746 type Work @default.
• W2159662746 sameAs 2159662746 @default.
• W2159662746 citedByCount "34" @default.
• W2159662746 countsByYear W21596627462012 @default.
• W2159662746 countsByYear W21596627462013 @default.
• W2159662746 countsByYear W21596627462014 @default.
• W2159662746 countsByYear W21596627462015 @default.
• W2159662746 countsByYear W21596627462016 @default.
• W2159662746 countsByYear W21596627462017 @default.
• W2159662746 countsByYear W21596627462019 @default.
• W2159662746 countsByYear W21596627462020 @default.
• W2159662746 countsByYear W21596627462021 @default.
• W2159662746 countsByYear W21596627462022 @default.
• W2159662746 countsByYear W21596627462023 @default.
• W2159662746 crossrefType "journal-article" @default.
• W2159662746 hasAuthorship W2159662746A5002982938 @default.
• W2159662746 hasAuthorship W2159662746A5017366317 @default.
• W2159662746 hasAuthorship W2159662746A5022132006 @default.
• W2159662746 hasAuthorship W2159662746A5038106053 @default.
• W2159662746 hasAuthorship W2159662746A5051664627 @default.
• W2159662746 hasAuthorship W2159662746A5057729977 @default.
• W2159662746 hasAuthorship W2159662746A5057764662 @default.
• W2159662746 hasAuthorship W2159662746A5058562840 @default.
• W2159662746 hasAuthorship W2159662746A5077466609 @default.
• W2159662746 hasAuthorship W2159662746A5079491393 @default.
• W2159662746 hasAuthorship W2159662746A5084405906 @default.
• W2159662746 hasBestOaLocation W21596627461 @default.
• W2159662746 hasConcept C126322002 @default.
• W2159662746 hasConcept C134018914 @default.
• W2159662746 hasConcept C2775850156 @default.
• W2159662746 hasConcept C2777090595 @default.
• W2159662746 hasConcept C2777391703 @default.
• W2159662746 hasConcept C2777468819 @default.
• W2159662746 hasConcept C2778319312 @default.
• W2159662746 hasConcept C2779877776 @default.
• W2159662746 hasConcept C2780972559 @default.
• W2159662746 hasConcept C515207424 @default.
• W2159662746 hasConcept C55493867 @default.
• W2159662746 hasConcept C555293320 @default.
• W2159662746 hasConcept C71924100 @default.
• W2159662746 hasConcept C84393581 @default.
• W2159662746 hasConcept C86803240 @default.

• next