Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159718801> ?p ?o ?g. }
- W2159718801 endingPage "1007" @default.
- W2159718801 startingPage "997" @default.
- W2159718801 abstract "In the rabbit model of electrically induced intimal thickening, the adherence processes of different leukocyte subsets as well as the functional significance of leukocyte invasion in the initial migration of smooth muscle cells (SMCs) into the intima were studied by using monoclonal antibody (MAb) 60.3 (directed to the leukocyte adherence glycoprotein CD18), a known potent inhibitor of leukocyte adhesive functions. In control carotid arteries exposed to two periods of electrical stimulation within 36 hours, leukocytes, including all granulocyte subsets, monocytes, and lymphocytes, invaded the cell-free subendothelium. Concomitantly, SMCs were observed to migrate from the media into the intima. In the MAb 60.3-treated rabbits, however, neutrophil emigration into the stimulated arteries was abolished, whereas mononuclear leukocyte accumulation in the intima was only partially inhibited, indicating a complete CD18-dependent mechanism for neutrophil extravasation and additional receptor-ligand systems for the emigration of mononuclear leukocytes. SMCs moved into the intima despite complete blockage of neutrophils and the reduced accumulation of mononuclear cells within the subendothelium after MAb administration. These results preclude neutrophils as initiators of SMC migration into the intima. The influence of mononuclear cells on the migratory behavior of SMCs in intimal thickening formation, however, needs further elucidation." @default.
- W2159718801 created "2016-06-24" @default.
- W2159718801 creator A5050393236 @default.
- W2159718801 creator A5079052878 @default.
- W2159718801 creator A5082034991 @default.
- W2159718801 date "1992-09-01" @default.
- W2159718801 modified "2023-09-27" @default.
- W2159718801 title "Inhibition of leukocyte extravasation with a monoclonal antibody to CD18 during formation of experimental intimal thickening in rabbit carotid arteries." @default.
- W2159718801 cites W1525310086 @default.
- W2159718801 cites W1539226901 @default.
- W2159718801 cites W1564695791 @default.
- W2159718801 cites W1570191167 @default.
- W2159718801 cites W1593349322 @default.
- W2159718801 cites W1966286149 @default.
- W2159718801 cites W1973485202 @default.
- W2159718801 cites W1974790290 @default.
- W2159718801 cites W1981413269 @default.
- W2159718801 cites W1982102375 @default.
- W2159718801 cites W1982256640 @default.
- W2159718801 cites W1989756421 @default.
- W2159718801 cites W1991512363 @default.
- W2159718801 cites W1996862503 @default.
- W2159718801 cites W2006432825 @default.
- W2159718801 cites W2008042118 @default.
- W2159718801 cites W2008424646 @default.
- W2159718801 cites W2015182412 @default.
- W2159718801 cites W2017669964 @default.
- W2159718801 cites W2023487115 @default.
- W2159718801 cites W2024634491 @default.
- W2159718801 cites W2031997121 @default.
- W2159718801 cites W2032207767 @default.
- W2159718801 cites W2035720710 @default.
- W2159718801 cites W2045724746 @default.
- W2159718801 cites W2046878557 @default.
- W2159718801 cites W2047277639 @default.
- W2159718801 cites W2050795431 @default.
- W2159718801 cites W2055184058 @default.
- W2159718801 cites W2063277519 @default.
- W2159718801 cites W2076832562 @default.
- W2159718801 cites W2083217753 @default.
- W2159718801 cites W2086487142 @default.
- W2159718801 cites W2087890016 @default.
- W2159718801 cites W2093737444 @default.
- W2159718801 cites W2094852775 @default.
- W2159718801 cites W2115131016 @default.
- W2159718801 cites W2116008315 @default.
- W2159718801 cites W2259392365 @default.
- W2159718801 cites W2316453626 @default.
- W2159718801 cites W2336184564 @default.
- W2159718801 cites W2406489691 @default.
- W2159718801 cites W2433556473 @default.
- W2159718801 cites W28826007 @default.
- W2159718801 cites W4211053163 @default.
- W2159718801 cites W4301861531 @default.
- W2159718801 doi "https://doi.org/10.1161/01.atv.12.9.997" @default.
- W2159718801 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1381958" @default.
- W2159718801 hasPublicationYear "1992" @default.
- W2159718801 type Work @default.
- W2159718801 sameAs 2159718801 @default.
- W2159718801 citedByCount "26" @default.
- W2159718801 countsByYear W21597188012014 @default.
- W2159718801 countsByYear W21597188012015 @default.
- W2159718801 countsByYear W21597188012017 @default.
- W2159718801 countsByYear W21597188012018 @default.
- W2159718801 countsByYear W21597188012020 @default.
- W2159718801 countsByYear W21597188012021 @default.
- W2159718801 crossrefType "journal-article" @default.
- W2159718801 hasAuthorship W2159718801A5050393236 @default.
- W2159718801 hasAuthorship W2159718801A5079052878 @default.
- W2159718801 hasAuthorship W2159718801A5082034991 @default.
- W2159718801 hasBestOaLocation W21597188011 @default.
- W2159718801 hasConcept C121332964 @default.
- W2159718801 hasConcept C137061746 @default.
- W2159718801 hasConcept C142724271 @default.
- W2159718801 hasConcept C153400128 @default.
- W2159718801 hasConcept C159654299 @default.
- W2159718801 hasConcept C185592680 @default.
- W2159718801 hasConcept C202751555 @default.
- W2159718801 hasConcept C203014093 @default.
- W2159718801 hasConcept C2779540182 @default.
- W2159718801 hasConcept C53122370 @default.
- W2159718801 hasConcept C542903549 @default.
- W2159718801 hasConcept C55493867 @default.
- W2159718801 hasConcept C71924100 @default.
- W2159718801 hasConcept C97355855 @default.
- W2159718801 hasConceptScore W2159718801C121332964 @default.
- W2159718801 hasConceptScore W2159718801C137061746 @default.
- W2159718801 hasConceptScore W2159718801C142724271 @default.
- W2159718801 hasConceptScore W2159718801C153400128 @default.
- W2159718801 hasConceptScore W2159718801C159654299 @default.
- W2159718801 hasConceptScore W2159718801C185592680 @default.
- W2159718801 hasConceptScore W2159718801C202751555 @default.
- W2159718801 hasConceptScore W2159718801C203014093 @default.
- W2159718801 hasConceptScore W2159718801C2779540182 @default.
- W2159718801 hasConceptScore W2159718801C53122370 @default.
- W2159718801 hasConceptScore W2159718801C542903549 @default.
- W2159718801 hasConceptScore W2159718801C55493867 @default.
- W2159718801 hasConceptScore W2159718801C71924100 @default.