FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159719613> ?p ?o ?g. }

• W2159719613 endingPage "2805" @default.
• W2159719613 startingPage "2800" @default.
• W2159719613 abstract "Small diffusible redox proteins facilitate electron transfer in respiration and photosynthesis by alternately binding to integral membrane proteins. Specific and transient complexes need to be formed between the redox partners to ensure fast turnover. In respiration, the mobile electron carrier cytochrome c shuttles electrons from the cytochrome bc1 complex to cytochrome c oxidase. Despite extensive studies of this fundamental step of energy metabolism, the structures of the respective electron transfer complexes were not known. Here we present the crystal structure of the complex between cytochrome c and the cytochrome bc1 complex from Saccharomyces cerevisiae. The complex was crystallized with the help of an antibody fragment, and its structure was determined at 2.97-A resolution. Cytochrome c is bound to subunit cytochrome c1 of the enzyme. The tight and specific interactions critical for electron transfer are mediated mainly by nonpolar forces. The close spatial arrangement of the c-type hemes unexpectedly suggests a direct and rapid heme-to-heme electron transfer at a calculated rate of up to 8.3 x 10(6) s(-1). Remarkably, cytochrome c binds to only one recognition site of the homodimeric multisubunit complex. Interestingly, the occupancy of quinone in the Qi site is higher in the monomer with bound cytochrome c, suggesting a coordinated binding and reduction of both electron-accepting substrates. Obviously, cytochrome c reduction by the cytochrome bc1 complex can be regulated in response to respiratory conditions." @default.
• W2159719613 created "2016-06-24" @default.
• W2159719613 creator A5005730211 @default.
• W2159719613 creator A5059146662 @default.
• W2159719613 date "2002-03-05" @default.
• W2159719613 modified "2023-10-02" @default.
• W2159719613 title "Crystal structure of the yeast cytochrome <i>bc</i> ₁ complex with its bound substrate cytochrome <i>c</i>" @default.
• W2159719613 cites W1495595397 @default.
• W2159719613 cites W1508808395 @default.
• W2159719613 cites W1523997495 @default.
• W2159719613 cites W1538745462 @default.
• W2159719613 cites W1539796472 @default.
• W2159719613 cites W1548336227 @default.
• W2159719613 cites W1595256727 @default.
• W2159719613 cites W1638874881 @default.
• W2159719613 cites W1675570769 @default.
• W2159719613 cites W1948683976 @default.
• W2159719613 cites W1980831979 @default.
• W2159719613 cites W1994441782 @default.
• W2159719613 cites W1995017064 @default.
• W2159719613 cites W1996607909 @default.
• W2159719613 cites W2002041204 @default.
• W2159719613 cites W2008003969 @default.
• W2159719613 cites W2013083986 @default.
• W2159719613 cites W2028231353 @default.
• W2159719613 cites W2029528758 @default.
• W2159719613 cites W2039254203 @default.
• W2159719613 cites W2042471904 @default.
• W2159719613 cites W2045942493 @default.
• W2159719613 cites W2048484224 @default.
• W2159719613 cites W2057981872 @default.
• W2159719613 cites W2061939056 @default.
• W2159719613 cites W2068276476 @default.
• W2159719613 cites W2072679497 @default.
• W2159719613 cites W2075770210 @default.
• W2159719613 cites W2076387836 @default.
• W2159719613 cites W2079167667 @default.
• W2159719613 cites W2080476827 @default.
• W2159719613 cites W2082190144 @default.
• W2159719613 cites W2092059009 @default.
• W2159719613 cites W2095898657 @default.
• W2159719613 cites W2106315897 @default.
• W2159719613 cites W2124540342 @default.
• W2159719613 cites W2134248388 @default.
• W2159719613 cites W2145412238 @default.
• W2159719613 cites W2170621128 @default.
• W2159719613 doi "https://doi.org/10.1073/pnas.052704699" @default.
• W2159719613 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/122428" @default.
• W2159719613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11880631" @default.
• W2159719613 hasPublicationYear "2002" @default.
• W2159719613 type Work @default.
• W2159719613 sameAs 2159719613 @default.
• W2159719613 citedByCount "319" @default.
• W2159719613 countsByYear W21597196132012 @default.
• W2159719613 countsByYear W21597196132013 @default.
• W2159719613 countsByYear W21597196132014 @default.
• W2159719613 countsByYear W21597196132015 @default.
• W2159719613 countsByYear W21597196132016 @default.
• W2159719613 countsByYear W21597196132017 @default.
• W2159719613 countsByYear W21597196132018 @default.
• W2159719613 countsByYear W21597196132019 @default.
• W2159719613 countsByYear W21597196132020 @default.
• W2159719613 countsByYear W21597196132021 @default.
• W2159719613 countsByYear W21597196132022 @default.
• W2159719613 countsByYear W21597196132023 @default.
• W2159719613 crossrefType "journal-article" @default.
• W2159719613 hasAuthorship W2159719613A5005730211 @default.
• W2159719613 hasAuthorship W2159719613A5059146662 @default.
• W2159719613 hasBestOaLocation W21597196132 @default.
• W2159719613 hasConcept C104292427 @default.
• W2159719613 hasConcept C104317684 @default.
• W2159719613 hasConcept C123249941 @default.
• W2159719613 hasConcept C123669783 @default.
• W2159719613 hasConcept C133166286 @default.
• W2159719613 hasConcept C14471203 @default.
• W2159719613 hasConcept C148292235 @default.
• W2159719613 hasConcept C171305022 @default.
• W2159719613 hasConcept C179104552 @default.
• W2159719613 hasConcept C181199279 @default.
• W2159719613 hasConcept C185592680 @default.
• W2159719613 hasConcept C24586158 @default.
• W2159719613 hasConcept C24840226 @default.
• W2159719613 hasConcept C2776217839 @default.
• W2159719613 hasConcept C2780768313 @default.
• W2159719613 hasConcept C28859421 @default.
• W2159719613 hasConcept C2909484822 @default.
• W2159719613 hasConcept C29311851 @default.
• W2159719613 hasConcept C55493867 @default.
• W2159719613 hasConcept C55904794 @default.
• W2159719613 hasConcept C71240020 @default.
• W2159719613 hasConcept C75297921 @default.
• W2159719613 hasConcept C75473681 @default.
• W2159719613 hasConcept C8010536 @default.
• W2159719613 hasConcept C82880906 @default.
• W2159719613 hasConceptScore W2159719613C104292427 @default.
• W2159719613 hasConceptScore W2159719613C104317684 @default.
• W2159719613 hasConceptScore W2159719613C123249941 @default.
• W2159719613 hasConceptScore W2159719613C123669783 @default.

• next