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- W2159780761 abstract "To identify HLA antigen associations with geriatric depression, the authors typed 36 elderly patients with major depression and, for comparison, 36 patients with Alzheimer-type dementia and 29 nondemented elderly controls. The frequency for antigen Aw32 was significantly higher in the group of patients with major depression (14%) than in the demented (0%) and control (3%) groups. The frequencies for antigens Aw32 (22%) and Bw51 (22%) were significantly higher in the subgroup of 23 patients with endogenous depression than in the demented (Aw32 = 0%; Bw51 = 11%) and the control (Aw32 = 3%; Bw51 = 0%) groups. Although these results were derived from a relatively small sample (n = 101) and become nonsignificant when corrected for multiple comparisons, they suggest that HLA antigen associations may be present for only certain depressive subtypes in geriatric depression. ( J Geriatr Psychiatry Neurol 1989;2:70-75)." @default.
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- W2159780761 date "1989-04-01" @default.
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- W2159780761 title "HLA Antigens in Depressed, Demented, and Nondemented Elderly" @default.
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- W2159780761 doi "https://doi.org/10.1177/089198878900200203" @default.
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