FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159878068> ?p ?o ?g. }

• W2159878068 endingPage "1263" @default.
• W2159878068 startingPage "1256" @default.
• W2159878068 abstract "Background: Tissue plasminogen activator (t‐PA) and plasminogen activator inhibitor type 1 (PAI‐1) are involved in the pathogenesis of periodontitis by controlling proteolytic events in the extracellular matrix. This study was designed to investigate the association of t‐PA and PAI‐1 gene polymorphisms with chronic periodontitis (CP). Methods: One hundred eighty‐nine subjects were included. Genomic DNA was obtained from the peripheral blood of 84 patients with CP and 105 periodontally healthy subjects. Polymerase chain reaction and endonuclease digestion was used to genotype the 4G/5G polymorphism in the promoter region of the PAI‐1 gene and the Alu‐repeat insertion (I)/deletion (D) polymorphism in intron 8 of the t‐PA gene. Results: The genotype distributions and allele frequencies of t‐PA polymorphism were not different between patients with CP and healthy subjects (24.7% I/I, 45.7% I/D, and 29.6% D/D and 30.3% I/I, 45.5% I/D, and 24.2% D/D, respectively; P >0.05). The t‐PA D allele frequency was similar in patients with CP (52.4%) and healthy subjects (46.5%). PAI‐1 genotype distribution in patients with CP (30.9% 4G/4G, 35.8% 4G/5G, and 33.3% 5G/5G) and healthy subjects (36.2% 4G/4G, 41.9% 4G/5G, and 21.9% 5G/5G) was also similar. The 4G allele frequency was not different between patients with CP (48.8%) and healthy subjects (57.1%) ( P >0.05). The 4G allele frequency in non‐smoking CP patients was significantly lower than in non‐smoking, healthy subjects (χ 2 = 4.201; P = 0.040). Non‐smoking CP patients also had a significantly lower percentage of 4G‐positive genotypes compared to non‐smoking healthy subjects (χ 2 = 5.046; P = 0.025). Conclusions: t‐PA or PAI‐1 genotypes are not associated with susceptibility to CP in Turkish subjects. Conversely, the 4G allele of the PAI‐1 gene could be related to a decreased susceptibility to CP in non‐smokers." @default.
• W2159878068 created "2016-06-24" @default.
• W2159878068 creator A5011971610 @default.
• W2159878068 creator A5012976447 @default.
• W2159878068 creator A5028661324 @default.
• W2159878068 creator A5033918328 @default.
• W2159878068 creator A5055212996 @default.
• W2159878068 creator A5065054489 @default.
• W2159878068 creator A5076174213 @default.
• W2159878068 date "2007-07-01" @default.
• W2159878068 modified "2023-10-17" @default.
• W2159878068 title "Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Gene Polymorphisms in Patients With Chronic Periodontitis" @default.
• W2159878068 cites W1505365469 @default.
• W2159878068 cites W1630061106 @default.
• W2159878068 cites W1950882931 @default.
• W2159878068 cites W1965430426 @default.
• W2159878068 cites W1991059254 @default.
• W2159878068 cites W1996346597 @default.
• W2159878068 cites W2005177731 @default.
• W2159878068 cites W2022694287 @default.
• W2159878068 cites W2027383668 @default.
• W2159878068 cites W2031018845 @default.
• W2159878068 cites W2072699133 @default.
• W2159878068 cites W2077967307 @default.
• W2159878068 cites W2082772723 @default.
• W2159878068 cites W2088325301 @default.
• W2159878068 cites W2089504298 @default.
• W2159878068 cites W2091153794 @default.
• W2159878068 cites W2103842148 @default.
• W2159878068 cites W2105886563 @default.
• W2159878068 cites W2107908226 @default.
• W2159878068 cites W2110701294 @default.
• W2159878068 cites W2110760852 @default.
• W2159878068 cites W2117053257 @default.
• W2159878068 cites W2117931787 @default.
• W2159878068 cites W2124671503 @default.
• W2159878068 cites W2126876991 @default.
• W2159878068 cites W2142952677 @default.
• W2159878068 cites W2153426201 @default.
• W2159878068 cites W2156731917 @default.
• W2159878068 cites W2157689730 @default.
• W2159878068 cites W2174784305 @default.
• W2159878068 cites W2614805886 @default.
• W2159878068 cites W53352658 @default.
• W2159878068 cites W79766069 @default.
• W2159878068 doi "https://doi.org/10.1902/jop.2007.060383" @default.
• W2159878068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17608581" @default.
• W2159878068 hasPublicationYear "2007" @default.
• W2159878068 type Work @default.
• W2159878068 sameAs 2159878068 @default.
• W2159878068 citedByCount "19" @default.
• W2159878068 countsByYear W21598780682012 @default.
• W2159878068 countsByYear W21598780682014 @default.
• W2159878068 countsByYear W21598780682019 @default.
• W2159878068 countsByYear W21598780682020 @default.
• W2159878068 countsByYear W21598780682021 @default.
• W2159878068 crossrefType "journal-article" @default.
• W2159878068 hasAuthorship W2159878068A5011971610 @default.
• W2159878068 hasAuthorship W2159878068A5012976447 @default.
• W2159878068 hasAuthorship W2159878068A5028661324 @default.
• W2159878068 hasAuthorship W2159878068A5033918328 @default.
• W2159878068 hasAuthorship W2159878068A5055212996 @default.
• W2159878068 hasAuthorship W2159878068A5065054489 @default.
• W2159878068 hasAuthorship W2159878068A5076174213 @default.
• W2159878068 hasConcept C104317684 @default.
• W2159878068 hasConcept C126322002 @default.
• W2159878068 hasConcept C135763542 @default.
• W2159878068 hasConcept C153911025 @default.
• W2159878068 hasConcept C180754005 @default.
• W2159878068 hasConcept C203014093 @default.
• W2159878068 hasConcept C2776572282 @default.
• W2159878068 hasConcept C2779337755 @default.
• W2159878068 hasConcept C2779679481 @default.
• W2159878068 hasConcept C2780385504 @default.
• W2159878068 hasConcept C2780675426 @default.
• W2159878068 hasConcept C2780942790 @default.
• W2159878068 hasConcept C37463918 @default.
• W2159878068 hasConcept C54355233 @default.
• W2159878068 hasConcept C71924100 @default.
• W2159878068 hasConcept C76252995 @default.
• W2159878068 hasConcept C86803240 @default.
• W2159878068 hasConceptScore W2159878068C104317684 @default.
• W2159878068 hasConceptScore W2159878068C126322002 @default.
• W2159878068 hasConceptScore W2159878068C135763542 @default.
• W2159878068 hasConceptScore W2159878068C153911025 @default.
• W2159878068 hasConceptScore W2159878068C180754005 @default.
• W2159878068 hasConceptScore W2159878068C203014093 @default.
• W2159878068 hasConceptScore W2159878068C2776572282 @default.
• W2159878068 hasConceptScore W2159878068C2779337755 @default.
• W2159878068 hasConceptScore W2159878068C2779679481 @default.
• W2159878068 hasConceptScore W2159878068C2780385504 @default.
• W2159878068 hasConceptScore W2159878068C2780675426 @default.
• W2159878068 hasConceptScore W2159878068C2780942790 @default.
• W2159878068 hasConceptScore W2159878068C37463918 @default.
• W2159878068 hasConceptScore W2159878068C54355233 @default.
• W2159878068 hasConceptScore W2159878068C71924100 @default.
• W2159878068 hasConceptScore W2159878068C76252995 @default.
• W2159878068 hasConceptScore W2159878068C86803240 @default.

• next