FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2159886305> ?p ?o ?g. }

• W2159886305 endingPage "2145" @default.
• W2159886305 startingPage "2145" @default.
• W2159886305 abstract "<b><i>Objective:</i></b> To determine whether volumes of hippocampus and amygdala are abnormal in people with autism. <b><i>Background:</i></b> Neuropathologic studies of the limbic system in autism have found decreased neuronal size, increased neuronal packing density, and decreased complexity of dendritic arbors in hippocampus, amygdala, and other limbic structures. These findings are suggestive of a developmental curtailment in the maturation of the neurons and neuropil. <b><i>Methods:</i></b> Measurement of hippocampus, amygdala, and total brain volumes from 1.5-mm coronal, spoiled gradient-recalled echo MRI scans in 14 non–mentally retarded autistic male adolescents and young adults and 14 individually matched, healthy community volunteers. <b><i>Results:</i></b> Amygdala volume was significantly smaller in the autistic subjects, both with (<i>p</i> = 0.006) and without (<i>p</i> = 0.01) correcting for total brain volume. Total brain volume and absolute hippocampal volume did not differ significantly between groups, but hippocampal volume, when corrected for total brain volume, was significantly reduced (<i>p</i> = 0.04) in the autistic subjects. <b><i>Conclusions:</i></b> There is a reduction in the volume of amygdala and hippocampus in people with autism, particularly in relation to total brain volume. The histopathology of autism suggests that these volume reductions are related to a reduction in dendritic tree and neuropil development, and likely reflect the underdevelopment of the neural connections of limbic structures with other parts of the brain, particularly cerebral cortex." @default.
• W2159886305 created "2016-06-24" @default.
• W2159886305 creator A5004702593 @default.
• W2159886305 creator A5006004425 @default.
• W2159886305 creator A5010132043 @default.
• W2159886305 creator A5010644944 @default.
• W2159886305 creator A5011715160 @default.
• W2159886305 creator A5053286583 @default.
• W2159886305 creator A5060548074 @default.
• W2159886305 creator A5087890631 @default.
• W2159886305 date "1999-12-01" @default.
• W2159886305 modified "2023-10-09" @default.
• W2159886305 title "MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adults" @default.
• W2159886305 cites W1512582702 @default.
• W2159886305 cites W1579305661 @default.
• W2159886305 cites W19462567 @default.
• W2159886305 cites W1974786952 @default.
• W2159886305 cites W1975228824 @default.
• W2159886305 cites W1980309199 @default.
• W2159886305 cites W1988246882 @default.
• W2159886305 cites W1989442204 @default.
• W2159886305 cites W1993621007 @default.
• W2159886305 cites W1998819381 @default.
• W2159886305 cites W2003230351 @default.
• W2159886305 cites W2016046043 @default.
• W2159886305 cites W2021783165 @default.
• W2159886305 cites W2024456521 @default.
• W2159886305 cites W2024655460 @default.
• W2159886305 cites W2035518691 @default.
• W2159886305 cites W2035541936 @default.
• W2159886305 cites W2036685176 @default.
• W2159886305 cites W2041309295 @default.
• W2159886305 cites W2044071327 @default.
• W2159886305 cites W2045001730 @default.
• W2159886305 cites W2053914476 @default.
• W2159886305 cites W2065083762 @default.
• W2159886305 cites W2076752136 @default.
• W2159886305 cites W2078633599 @default.
• W2159886305 cites W2081713212 @default.
• W2159886305 cites W2084550269 @default.
• W2159886305 cites W2086322201 @default.
• W2159886305 cites W2089204366 @default.
• W2159886305 cites W2094304570 @default.
• W2159886305 cites W2123739801 @default.
• W2159886305 cites W2139399313 @default.
• W2159886305 cites W2147147373 @default.
• W2159886305 cites W619078857 @default.
• W2159886305 doi "https://doi.org/10.1212/wnl.53.9.2145" @default.
• W2159886305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10599796" @default.
• W2159886305 hasPublicationYear "1999" @default.
• W2159886305 type Work @default.
• W2159886305 sameAs 2159886305 @default.
• W2159886305 citedByCount "461" @default.
• W2159886305 countsByYear W21598863052012 @default.
• W2159886305 countsByYear W21598863052013 @default.
• W2159886305 countsByYear W21598863052014 @default.
• W2159886305 countsByYear W21598863052015 @default.
• W2159886305 countsByYear W21598863052016 @default.
• W2159886305 countsByYear W21598863052017 @default.
• W2159886305 countsByYear W21598863052018 @default.
• W2159886305 countsByYear W21598863052019 @default.
• W2159886305 countsByYear W21598863052020 @default.
• W2159886305 countsByYear W21598863052021 @default.
• W2159886305 countsByYear W21598863052022 @default.
• W2159886305 countsByYear W21598863052023 @default.
• W2159886305 crossrefType "journal-article" @default.
• W2159886305 hasAuthorship W2159886305A5004702593 @default.
• W2159886305 hasAuthorship W2159886305A5006004425 @default.
• W2159886305 hasAuthorship W2159886305A5010132043 @default.
• W2159886305 hasAuthorship W2159886305A5010644944 @default.
• W2159886305 hasAuthorship W2159886305A5011715160 @default.
• W2159886305 hasAuthorship W2159886305A5053286583 @default.
• W2159886305 hasAuthorship W2159886305A5060548074 @default.
• W2159886305 hasAuthorship W2159886305A5087890631 @default.
• W2159886305 hasConcept C118552586 @default.
• W2159886305 hasConcept C126322002 @default.
• W2159886305 hasConcept C126838900 @default.
• W2159886305 hasConcept C143409427 @default.
• W2159886305 hasConcept C148762608 @default.
• W2159886305 hasConcept C15744967 @default.
• W2159886305 hasConcept C169760540 @default.
• W2159886305 hasConcept C205778803 @default.
• W2159886305 hasConcept C2776993930 @default.
• W2159886305 hasConcept C2777831001 @default.
• W2159886305 hasConcept C2779144063 @default.
• W2159886305 hasConcept C2781161787 @default.
• W2159886305 hasConcept C529278444 @default.
• W2159886305 hasConcept C541082541 @default.
• W2159886305 hasConcept C65835030 @default.
• W2159886305 hasConcept C71924100 @default.
• W2159886305 hasConceptScore W2159886305C118552586 @default.
• W2159886305 hasConceptScore W2159886305C126322002 @default.
• W2159886305 hasConceptScore W2159886305C126838900 @default.
• W2159886305 hasConceptScore W2159886305C143409427 @default.
• W2159886305 hasConceptScore W2159886305C148762608 @default.
• W2159886305 hasConceptScore W2159886305C15744967 @default.
• W2159886305 hasConceptScore W2159886305C169760540 @default.
• W2159886305 hasConceptScore W2159886305C205778803 @default.

• next