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• W2159904093 abstract "A novel visual method for K+ detection is developed utilizing a K+-sensitive G-quadruplex DNA named PS5.M as the sensing element. In the absence of K+, PS5.M is in a random coil state and does not bind hemin. Upon addition of K+, PS5.M folds into the quadruplex structure stabilized by K+. Such quadruplex structure is able to bind hemin to form the hemin-G-quadruplex DNAzyme that catalyzes the H2O2-mediated oxidation of colorless 3,3′,5,5′-tetramethylbenzidine to the blue product. Under the optimal conditions, the color change can be clearly observed with the naked eye in the concentration range from 2 to 1000 μM. Through this facile approach, K+ can be detected down to 2 μM, with high selectivity against other cations. In view of its simplicity, sensitivity and specificity, our developed visual method for K+ detection would potentially be utilized for bioassays and K+-sensitive test paper." @default.
• W2159904093 created "2016-06-24" @default.
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• W2159904093 date "2010-01-01" @default.
• W2159904093 modified "2023-09-25" @default.
• W2159904093 title "Potassium-sensitive G-quadruplexDNA for sensitive visible potassium detection" @default.
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• W2159904093 doi "https://doi.org/10.1039/b913036e" @default.
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