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- W2160019762 abstract "The penetration of 3H2O, [14C]antipyrine, [14C]-inulin, and 125I- into the whole gland and follicular luminal fluid of the turtle thyroid was studied by measuring the whole thyroid tissue and sampling the colloid in the lumen by micropipettes. 3H2O equilibrated in the luminal water within 0.5 h. Linear regression analysis of the long half-life component of the 3H2O uptake curve of whole thyroid gland showed that this component had a t½ of 10.7 min and a y-intercept of 51.9%; it is a measure of the luminal volume. The [14C]inulin interstitial space was 13.8%. The difference (27.8%) between the slow component intercept value of the 3H2O uptake curve and the total water content is a measure of the combined interstitial and cellular water volumes; the cellular volume is thus 14% (27.8–13.8%). Analysis of the uptake curves for 125I- penetration into the luminal fluid of methimazole-treated turtles demonstrated that there was only one component, with a t½ of 9.2 h for control and 10.5 h for TSH-treated animals...." @default.
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- W2160019762 date "1981-06-01" @default.
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- W2160019762 title "Compartmentation in the Turtle Thyroid: Water and Iodide Distribution*" @default.
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- W2160019762 doi "https://doi.org/10.1210/endo-108-6-2200" @default.
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