FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2160095533> ?p ?o ?g. }

• W2160095533 endingPage "357" @default.
• W2160095533 startingPage "349" @default.
• W2160095533 abstract "Controversy exists regarding the causative role of dietary fructose in obesity and fatty liver diseases. Clinical trials have indicated that negative health consequences may occur only when fructose is consumed within excess calories. Animal studies have suggested that fructose impairs intestinal integrity and leads to hepatic steatosis (HS).We assessed nonhuman primates after chronic ad libitum and short-term calorically controlled consumption of a high-fructose (HFr), low-fat diet (24% of calories). Microbial translocation (MT), microbiome, and metabolic health indexes were evaluated.Seventeen monkeys fed 0.3–7 y of an HFr ad libitum diet were compared with 10 monkeys fed a low-fructose, low-fat diet (control). Ten middle-aged, weight-stable, fructose-naive monkeys were stratified into HFr and control groups fed for 6 wk at caloric amounts required to maintain weight stability. Metabolic endpoints, feces, liver, small and large intestinal biopsies, and portal blood samples were collected.Monkeys allowed ad libitum HFr developed HS in contrast to the control diet, and the extent of ectopic fat was related to the duration of feeding. Diabetes incidence also increased. Monkeys that consumed calorically controlled HFr showed significant increases in biomarkers of liver damage, endotoxemia, and MT indexes and a trend for greater hepatitis that was related to MT; however, HS did not develop.Even in the absence of weight gain, fructose rapidly causes liver damage that we suggest is secondary to endotoxemia and MT. HS relates to the duration of fructose consumption and total calories consumed. These data support fructose inducing both MT and ectopic fat deposition in primates." @default.
• W2160095533 created "2016-06-24" @default.
• W2160095533 creator A5000603458 @default.
• W2160095533 creator A5004693200 @default.
• W2160095533 creator A5006510210 @default.
• W2160095533 creator A5029240202 @default.
• W2160095533 creator A5033638916 @default.
• W2160095533 creator A5057451707 @default.
• W2160095533 creator A5069450318 @default.
• W2160095533 date "2013-06-19" @default.
• W2160095533 modified "2023-10-10" @default.
• W2160095533 title "Dietary fructose induces endotoxemia and hepatic injury in calorically controlled primates" @default.
• W2160095533 cites W1831268717 @default.
• W2160095533 cites W1932966132 @default.
• W2160095533 cites W1975256521 @default.
• W2160095533 cites W1976040781 @default.
• W2160095533 cites W1977040679 @default.
• W2160095533 cites W1978968559 @default.
• W2160095533 cites W1983586642 @default.
• W2160095533 cites W1987184081 @default.
• W2160095533 cites W1987933053 @default.
• W2160095533 cites W1990061996 @default.
• W2160095533 cites W1994261934 @default.
• W2160095533 cites W2001464035 @default.
• W2160095533 cites W2005151377 @default.
• W2160095533 cites W2015703748 @default.
• W2160095533 cites W2018124948 @default.
• W2160095533 cites W2030196870 @default.
• W2160095533 cites W2031820227 @default.
• W2160095533 cites W2036047239 @default.
• W2160095533 cites W2058178552 @default.
• W2160095533 cites W2059251195 @default.
• W2160095533 cites W2063041586 @default.
• W2160095533 cites W2065605458 @default.
• W2160095533 cites W2070197168 @default.
• W2160095533 cites W2070535353 @default.
• W2160095533 cites W2077963393 @default.
• W2160095533 cites W2085097924 @default.
• W2160095533 cites W2088170171 @default.
• W2160095533 cites W2091770605 @default.
• W2160095533 cites W2102920953 @default.
• W2160095533 cites W2107040151 @default.
• W2160095533 cites W2110569929 @default.
• W2160095533 cites W2113024584 @default.
• W2160095533 cites W2118964248 @default.
• W2160095533 cites W2120397203 @default.
• W2160095533 cites W2121562893 @default.
• W2160095533 cites W2124755555 @default.
• W2160095533 cites W2129917444 @default.
• W2160095533 cites W2134310566 @default.
• W2160095533 cites W2146966453 @default.
• W2160095533 cites W2147163488 @default.
• W2160095533 cites W2148956702 @default.
• W2160095533 cites W2154635249 @default.
• W2160095533 cites W2165857119 @default.
• W2160095533 cites W2169133380 @default.
• W2160095533 cites W2169834902 @default.
• W2160095533 cites W2237737651 @default.
• W2160095533 doi "https://doi.org/10.3945/ajcn.112.057331" @default.
• W2160095533 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3712547" @default.
• W2160095533 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23783298" @default.
• W2160095533 hasPublicationYear "2013" @default.
• W2160095533 type Work @default.
• W2160095533 sameAs 2160095533 @default.
• W2160095533 citedByCount "87" @default.
• W2160095533 countsByYear W21600955332013 @default.
• W2160095533 countsByYear W21600955332014 @default.
• W2160095533 countsByYear W21600955332015 @default.
• W2160095533 countsByYear W21600955332016 @default.
• W2160095533 countsByYear W21600955332017 @default.
• W2160095533 countsByYear W21600955332018 @default.
• W2160095533 countsByYear W21600955332019 @default.
• W2160095533 countsByYear W21600955332020 @default.
• W2160095533 countsByYear W21600955332021 @default.
• W2160095533 countsByYear W21600955332022 @default.
• W2160095533 countsByYear W21600955332023 @default.
• W2160095533 crossrefType "journal-article" @default.
• W2160095533 hasAuthorship W2160095533A5000603458 @default.
• W2160095533 hasAuthorship W2160095533A5004693200 @default.
• W2160095533 hasAuthorship W2160095533A5006510210 @default.
• W2160095533 hasAuthorship W2160095533A5029240202 @default.
• W2160095533 hasAuthorship W2160095533A5033638916 @default.
• W2160095533 hasAuthorship W2160095533A5057451707 @default.
• W2160095533 hasAuthorship W2160095533A5069450318 @default.
• W2160095533 hasBestOaLocation W21600955331 @default.
• W2160095533 hasConcept C104317684 @default.
• W2160095533 hasConcept C109297637 @default.
• W2160095533 hasConcept C126322002 @default.
• W2160095533 hasConcept C134018914 @default.
• W2160095533 hasConcept C2776175330 @default.
• W2160095533 hasConcept C2776970464 @default.
• W2160095533 hasConcept C2778772119 @default.
• W2160095533 hasConcept C2779134260 @default.
• W2160095533 hasConcept C2779306644 @default.
• W2160095533 hasConcept C2779772378 @default.
• W2160095533 hasConcept C31903555 @default.
• W2160095533 hasConcept C40438245 @default.
• W2160095533 hasConcept C42407357 @default.

• next