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- W2160127049 endingPage "3415" @default.
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- W2160127049 abstract "ABSTRACT Escherichia coli strains that cause nonbloody diarrhea in infants are known to present three distinct patterns of adherence to epithelial cells, namely, localized (LA), diffuse (DA), and aggregative (AA) adherence. Strains with LA (typical Enteropathogenic Escherichia coli [EPEC]) are well recognized as a cause of secretory diarrhea, but the role of strains with DA (DAEC) is controversial, and strains with AA (EAEC) have been more frequently related to persistent diarrhea whereas its relationship with acute diarrhea is not well defined. To determine the relationship of the different types of E. coli adherence patterns with acute diarrhea (lasting less than 14 days) and persistent diarrhea (lasting more than 14 days) in São Paulo, Brazil, we studied stool specimens from 40 infants under 1 year of age with diarrhea and 40 age-matched control infants without any gastrointestinal symptoms. Twenty-eight (35.0%) of eighty cases yielded adherent E. coli (HEp-2 cells). Strains with localized and aggregative adherence were associated with acute and persistent diarrhea. A total of 11.2% of the adherent strains were typical EPEC serotypes and hybridized with the enteroadherence factor probe; 5.0% were EAEC and hybridized with the EAEC probe. DAEC strains were isolated from 10.0% of patients and 7.5% of controls and did not hybridize with the two probes used ( daaC and AIDA-I). Strains with a localized adherence-like pattern (atypical EPEC) were found significantly more frequently ( P = 0.028) in cultures from children with diarrhea (17.5%) than in controls (2.5%)." @default.
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- W2160127049 date "1999-07-01" @default.
- W2160127049 modified "2023-10-01" @default.
- W2160127049 title "A Localized Adherence-Like Pattern as a Second Pattern of Adherence of Classic Enteropathogenic <i>Escherichia coli</i> to HEp-2 Cells That Is Associated with Infantile Diarrhea" @default.
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- W2160127049 doi "https://doi.org/10.1128/iai.67.7.3410-3415.1999" @default.
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