Matches in SemOpenAlex for { <https://semopenalex.org/work/W2160147998> ?p ?o ?g. }
- W2160147998 endingPage "98" @default.
- W2160147998 startingPage "93" @default.
- W2160147998 abstract "The pig (Sus scrofus) is a valuable animal for modeling human brain diseases. When evaluating animal models of many human brain disorders cognitive testing is crucial, but the pig's ability to learn the typical types of tasks used in neuropsychological testing of other species is largely unknown. The present study is the first study to evaluate the pig's ability to learn the Delayed Non-Match to Sample (DNMS) task. The pigs were trained in a maze on a spatial version of the DNMS task. Initially, the pigs were trained with a 60s delay interval between sample and test phases, and we found that the pigs required an average of 144 trials to reach criterion for learning the task, which is similar to macaque monkeys. We also found that pigs, in contrast to rats, do not have a natural tendency to alternate in their choices in the task. To evaluate the sensitivity to reduced memory function longer delay intervals (300 s and 900 s) and a scopolamine challenge were introduced. In our test condition we found a significant effect of longer delay intervals (F(2,21)=34.43, P<0.0001) and of scopolamine (F(1,14)=14.28, P=0.002) on the number of correct choices in the task. We conclude that the Göttingen minipig can solve the spatial DNMS task and that the task is sensitive to both increasing delay intervals and to scopolamine." @default.
- W2160147998 created "2016-06-24" @default.
- W2160147998 creator A5012414602 @default.
- W2160147998 creator A5015895924 @default.
- W2160147998 creator A5019495161 @default.
- W2160147998 creator A5027635886 @default.
- W2160147998 creator A5036468991 @default.
- W2160147998 creator A5071961187 @default.
- W2160147998 date "2009-01-01" @default.
- W2160147998 modified "2023-10-18" @default.
- W2160147998 title "A novel spatial Delayed Non-Match to Sample (DNMS) task in the Göttingen minipig" @default.
- W2160147998 cites W144891513 @default.
- W2160147998 cites W1556514691 @default.
- W2160147998 cites W1964191808 @default.
- W2160147998 cites W1969670050 @default.
- W2160147998 cites W1975068250 @default.
- W2160147998 cites W1978013584 @default.
- W2160147998 cites W1981818046 @default.
- W2160147998 cites W1983870428 @default.
- W2160147998 cites W1991033366 @default.
- W2160147998 cites W1994067502 @default.
- W2160147998 cites W2000097034 @default.
- W2160147998 cites W2001285978 @default.
- W2160147998 cites W2009449638 @default.
- W2160147998 cites W2011442470 @default.
- W2160147998 cites W2011769309 @default.
- W2160147998 cites W2013089722 @default.
- W2160147998 cites W2013854477 @default.
- W2160147998 cites W2014412068 @default.
- W2160147998 cites W2017587618 @default.
- W2160147998 cites W2030654758 @default.
- W2160147998 cites W2034232761 @default.
- W2160147998 cites W2047622680 @default.
- W2160147998 cites W2047993363 @default.
- W2160147998 cites W2060513591 @default.
- W2160147998 cites W2062832380 @default.
- W2160147998 cites W2071197145 @default.
- W2160147998 cites W2082769137 @default.
- W2160147998 cites W2091786477 @default.
- W2160147998 cites W2137022539 @default.
- W2160147998 cites W2150474596 @default.
- W2160147998 cites W2153821084 @default.
- W2160147998 cites W2154618565 @default.
- W2160147998 cites W2537514301 @default.
- W2160147998 cites W4238114310 @default.
- W2160147998 doi "https://doi.org/10.1016/j.bbr.2008.07.019" @default.
- W2160147998 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18706937" @default.
- W2160147998 hasPublicationYear "2009" @default.
- W2160147998 type Work @default.
- W2160147998 sameAs 2160147998 @default.
- W2160147998 citedByCount "14" @default.
- W2160147998 countsByYear W21601479982012 @default.
- W2160147998 countsByYear W21601479982014 @default.
- W2160147998 countsByYear W21601479982015 @default.
- W2160147998 countsByYear W21601479982018 @default.
- W2160147998 countsByYear W21601479982022 @default.
- W2160147998 crossrefType "journal-article" @default.
- W2160147998 hasAuthorship W2160147998A5012414602 @default.
- W2160147998 hasAuthorship W2160147998A5015895924 @default.
- W2160147998 hasAuthorship W2160147998A5019495161 @default.
- W2160147998 hasAuthorship W2160147998A5027635886 @default.
- W2160147998 hasAuthorship W2160147998A5036468991 @default.
- W2160147998 hasAuthorship W2160147998A5071961187 @default.
- W2160147998 hasConcept C138496976 @default.
- W2160147998 hasConcept C14216870 @default.
- W2160147998 hasConcept C154945302 @default.
- W2160147998 hasConcept C15744967 @default.
- W2160147998 hasConcept C162324750 @default.
- W2160147998 hasConcept C169760540 @default.
- W2160147998 hasConcept C169900460 @default.
- W2160147998 hasConcept C180747234 @default.
- W2160147998 hasConcept C187736073 @default.
- W2160147998 hasConcept C2776502983 @default.
- W2160147998 hasConcept C2778576352 @default.
- W2160147998 hasConcept C2778950215 @default.
- W2160147998 hasConcept C2780451532 @default.
- W2160147998 hasConcept C41008148 @default.
- W2160147998 hasConcept C41690226 @default.
- W2160147998 hasConcept C548259974 @default.
- W2160147998 hasConcept C71924100 @default.
- W2160147998 hasConcept C86803240 @default.
- W2160147998 hasConcept C98274493 @default.
- W2160147998 hasConceptScore W2160147998C138496976 @default.
- W2160147998 hasConceptScore W2160147998C14216870 @default.
- W2160147998 hasConceptScore W2160147998C154945302 @default.
- W2160147998 hasConceptScore W2160147998C15744967 @default.
- W2160147998 hasConceptScore W2160147998C162324750 @default.
- W2160147998 hasConceptScore W2160147998C169760540 @default.
- W2160147998 hasConceptScore W2160147998C169900460 @default.
- W2160147998 hasConceptScore W2160147998C180747234 @default.
- W2160147998 hasConceptScore W2160147998C187736073 @default.
- W2160147998 hasConceptScore W2160147998C2776502983 @default.
- W2160147998 hasConceptScore W2160147998C2778576352 @default.
- W2160147998 hasConceptScore W2160147998C2778950215 @default.
- W2160147998 hasConceptScore W2160147998C2780451532 @default.
- W2160147998 hasConceptScore W2160147998C41008148 @default.
- W2160147998 hasConceptScore W2160147998C41690226 @default.
- W2160147998 hasConceptScore W2160147998C548259974 @default.