FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2160149360> ?p ?o ?g. }

• W2160149360 endingPage "141" @default.
• W2160149360 startingPage "129" @default.
• W2160149360 abstract "Xylem development is a process of xylem cell terminal differentiation that includes initial cell division, cell expansion, secondary cell wall formation and programmed cell death (PCD). PCD in plants and apoptosis in animals share many common characteristics. Caspase-3, which displays Asp-Glu-Val-Asp (DEVD) specificity, is a crucial executioner during animal cells apoptosis. Although a gene orthologous to caspase-3 is absent in plants, caspase-3-like activity is involved in many cases of PCD and developmental processes. However, there is no direct evidence that caspase-3-like activity exists in xylem cell death. In this study, we showed that caspase-3-like activity is present and is associated with secondary xylem development in Populus tomentosa. The protease responsible for the caspase-3-like activity was purified from poplar secondary xylem using hydrophobic interaction chromatography (HIC), Q anion exchange chromatography and gel filtration chromatography. After identification by liquid chromatography-tandem mass spectrometry (LC-MS/MS), it was revealed that the 20S proteasome (20SP) was responsible for the caspase-3-like activity in secondary xylem development. In poplar 20SP, there are seven α subunits encoded by 12 genes and seven β subunits encoded by 12 genes. Pharmacological assays showed that Ac-DEVD-CHO, a caspase-3 inhibitor, suppressed xylem differentiation in the veins of Arabidopsis cotyledons. Furthermore, clasto-lactacystin β-lactone, a proteasome inhibitor, inhibited PCD of tracheary element in a VND6-induced Arabidopsis xylogenic culture. In conclusion, the 20S proteasome is responsible for caspase-3-like activity and is involved in xylem development." @default.
• W2160149360 created "2016-06-24" @default.
• W2160149360 creator A5020365606 @default.
• W2160149360 creator A5030561069 @default.
• W2160149360 creator A5048807497 @default.
• W2160149360 creator A5065657049 @default.
• W2160149360 creator A5067786876 @default.
• W2160149360 creator A5068713582 @default.
• W2160149360 date "2012-07-19" @default.
• W2160149360 modified "2023-10-10" @default.
• W2160149360 title "The proteasome is responsible for caspase-3-like activity during xylem development" @default.
• W2160149360 cites W1518300058 @default.
• W2160149360 cites W1962828345 @default.
• W2160149360 cites W1964602059 @default.
• W2160149360 cites W1965749819 @default.
• W2160149360 cites W1969204366 @default.
• W2160149360 cites W1969242049 @default.
• W2160149360 cites W1981564867 @default.
• W2160149360 cites W1986069582 @default.
• W2160149360 cites W1986070121 @default.
• W2160149360 cites W1988518686 @default.
• W2160149360 cites W1996723961 @default.
• W2160149360 cites W2000708366 @default.
• W2160149360 cites W2002821316 @default.
• W2160149360 cites W2005715606 @default.
• W2160149360 cites W2007517675 @default.
• W2160149360 cites W2010659528 @default.
• W2160149360 cites W2011984248 @default.
• W2160149360 cites W2013232866 @default.
• W2160149360 cites W2013258134 @default.
• W2160149360 cites W2013342444 @default.
• W2160149360 cites W2016151751 @default.
• W2160149360 cites W2024077782 @default.
• W2160149360 cites W2024548275 @default.
• W2160149360 cites W2040521994 @default.
• W2160149360 cites W2042198408 @default.
• W2160149360 cites W2042946762 @default.
• W2160149360 cites W2044513713 @default.
• W2160149360 cites W2046726975 @default.
• W2160149360 cites W2047704490 @default.
• W2160149360 cites W2049225661 @default.
• W2160149360 cites W2053461401 @default.
• W2160149360 cites W2059962672 @default.
• W2160149360 cites W2068600835 @default.
• W2160149360 cites W2075888166 @default.
• W2160149360 cites W2076822243 @default.
• W2160149360 cites W2086230817 @default.
• W2160149360 cites W2087715410 @default.
• W2160149360 cites W2088840585 @default.
• W2160149360 cites W2090951206 @default.
• W2160149360 cites W2099382705 @default.
• W2160149360 cites W2105301929 @default.
• W2160149360 cites W2106906885 @default.
• W2160149360 cites W2109396083 @default.
• W2160149360 cites W2109664841 @default.
• W2160149360 cites W2116247595 @default.
• W2160149360 cites W2117093778 @default.
• W2160149360 cites W2117368380 @default.
• W2160149360 cites W2119278722 @default.
• W2160149360 cites W2119718767 @default.
• W2160149360 cites W2121349454 @default.
• W2160149360 cites W2121824686 @default.
• W2160149360 cites W2122612108 @default.
• W2160149360 cites W2123942875 @default.
• W2160149360 cites W2127888098 @default.
• W2160149360 cites W2128262451 @default.
• W2160149360 cites W2128474899 @default.
• W2160149360 cites W2132356542 @default.
• W2160149360 cites W2132583664 @default.
• W2160149360 cites W2134374338 @default.
• W2160149360 cites W2146016369 @default.
• W2160149360 cites W2148386788 @default.
• W2160149360 cites W2153728340 @default.
• W2160149360 cites W2154932224 @default.
• W2160149360 cites W2155796246 @default.
• W2160149360 cites W2157398883 @default.
• W2160149360 cites W2165929388 @default.
• W2160149360 cites W2237993019 @default.
• W2160149360 cites W2284464544 @default.
• W2160149360 cites W2325707043 @default.
• W2160149360 cites W4252826354 @default.
• W2160149360 cites W67715254 @default.
• W2160149360 doi "https://doi.org/10.1111/j.1365-313x.2012.05070.x" @default.
• W2160149360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22680239" @default.
• W2160149360 hasPublicationYear "2012" @default.
• W2160149360 type Work @default.
• W2160149360 sameAs 2160149360 @default.
• W2160149360 citedByCount "78" @default.
• W2160149360 countsByYear W21601493602013 @default.
• W2160149360 countsByYear W21601493602014 @default.
• W2160149360 countsByYear W21601493602015 @default.
• W2160149360 countsByYear W21601493602016 @default.
• W2160149360 countsByYear W21601493602017 @default.
• W2160149360 countsByYear W21601493602018 @default.
• W2160149360 countsByYear W21601493602019 @default.
• W2160149360 countsByYear W21601493602020 @default.
• W2160149360 countsByYear W21601493602021 @default.
• W2160149360 countsByYear W21601493602022 @default.

• next