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- W2160257890 abstract "The spatial resolution of fluorescence molecular imaging is a critical issue for the success of the technique in biomedical applications. One important method for increasing the imaging resolution is to utilize multi-photon emissions. In this study, we thoroughly investigate the potential of the multi-photon upconversion emissions from rare-earth-doped upconverting nanoparticles for the improvement in spatial resolution of diffuse optical imaging. It is found that the imaging resolution is increased by a factor of 1.45 through employing two-photon upconversion emission compared with using the linear emission, and can be further elevated by a factor of 1.23 by using three-photon upconversion emission. In addition, we demonstrate that the pulsed excitation approach holds the promise of overcoming the low quantum yield associated with the high-order upconversion emissions." @default.
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- W2160257890 date "2014-07-15" @default.
- W2160257890 modified "2023-10-16" @default.
- W2160257890 title "Potential of multi-photon upconversion emissions for fluorescence diffuse optical imaging" @default.
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- W2160257890 doi "https://doi.org/10.1364/oe.22.017782" @default.
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