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- W2160326640 abstract "Abstract Objective: To evaluate the effects of dietary boron on bone regeneration in rabbits in response to expansion of the midpalatal suture during different retention periods. Materials and Methods: Twenty-eight 12-week-old New Zealand white male rabbits were separated into four equal groups: group 1 (B+10) and group 2 (B−10) had retention periods of 10 days with or without boron intake, respectively. Group 3 (B+20, with boron) and group 4 (B−20, without boron) were retained for 20 days. All groups had a 5-day expansion period. For both B+ groups, boron was prepared in distilled water and given to the rabbits during their (1) nursery phase (40 days), (2) expansion phase, and (3) retention period at a dosage of 3 mg/kg daily by oral gavage. Bone regeneration in the midpalatal suture was evaluated by a bone histomorphometric method, and the mineralized area (Md.Ar), fibrosis area (Fb.Ar), mineralized area/fibrosis area (Md.Ar/Fb.Ar), bone area (B.Ar) and osteoblast number (N.Ob) parameters were evaluated. Results: Statistical analysis showed significant differences between groups for all investigated measurements. Md.Ar (P < .01), Md.Ar/Fb.Ar (P < .001), B.Ar (P < .01), and N.Ob (P < .01) parameters were increased and Fb.Ar (P < .01) was decreased in groups B+10 and B+20. No significant differences were observed during an additional 10-day retention period in all groups (P < .05). Conclusions: Boron has a positive effect on the early phase of bone regeneration of the midpalatal suture in response to expansion and may be beneficial in routine maxillary expansion procedures." @default.
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- W2160326640 date "2009-09-01" @default.
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- W2160326640 title "Stimulation of Bone Formation by Dietary Boron in an Orthopedically Expanded Suture in Rabbits" @default.
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- W2160326640 doi "https://doi.org/10.2319/112708-604.1" @default.
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