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- W21603905 abstract "A novel family of non-nucleoside reverse transcriptase inhibitors (NNRTIs) active at submicromolar concentrations was discovered. The new derivatives are 1-[2-(diarylmethoxy)ethyl]imidazoles bearing substituents both at benzene and imidazole rings. The most potent derivatives were those having nitro and methyl groups as substituents in the imidazole ring. Among 10 test derivatives compound 6d was found to be as potent as nevirapine and was selected as a lead for further studies." @default.
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- W21603905 date "2000-02-01" @default.
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- W21603905 title "1-[2-(Diphenylmethoxy)ethyl]-2-methyl-5-nitroimidazole" @default.
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- W21603905 doi "https://doi.org/10.1016/s0960-894x(99)00664-2" @default.
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