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- W2160408355 abstract "Summary Objective: To assess the relative importanceof age and maternal antibodies on antibodyresponses of neonatal piglets to a commercial Mycoplasma hyopneumoniae vaccine.Methods: Piglets from 20 sows in each oftwo commercial swine operations (withserological evidence of M hyopneumoniae exposure) were vaccinated once at 2, 3, or4 weeks of age with an M hyopneumoniae bacterin, or were nonvaccinated controls.Serum IgG antibodies were assayed byELISA, using surface antigens of Mhyopneumoniae , in serum samples collectedfrom pigs in the first week of life and atprevaccination, 3 weeks postvaccination,and 2.5 months of age. Sows were vacci-nated against Mhyopneumoniae in Herd B,but not in Herd A.Results: In Herd A, piglets had moderatetiters of maternal antibodies. Vaccinatedpigs had significantly higher antibodyresponses than nonvaccinates. Higherprevaccination titers were associated withlower responses. Age at vaccination was notassociated with response to vaccination. InHerd B, piglets had high titers of maternalantibodies. Antibody titers of vaccinatedpigs did not decline as rapidly as those ofnonvaccinated pigs, and vaccinates hadhigher titers at 2.5 months of age.Implications: Titer of maternal antibodies,but not age (ie, immaturity of immunefunction), is a major concern when pigletsare vaccinated against" @default.
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- W2160408355 date "2004-01-01" @default.
- W2160408355 modified "2023-09-26" @default.
- W2160408355 title "Influence of age and maternal antibodies on antibody responses of neonatal piglets vaccinated against Mycoplasma hyopneumoniae" @default.
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