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• W2160818462 abstract "ABSTRACT We evaluated the pharmacokinetics and safety of the antimicrobial agent triclosan after dermal application of a 2% triclosan-containing cream to six volunteers. Percutaneous absorption calculated from urinary excretion was 5.9% ± 2.1% of the dose (mean ± standard deviation). The amount absorbed suggests that daily application of a standard adult dose would result in a systemic exposure 890 times lower than the relevant no-observed-adverse-effect level. Triclosan can be considered safe for use in hydrophobic creams." @default.
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• W2160818462 date "2010-01-01" @default.
• W2160818462 modified "2023-09-27" @default.
• W2160818462 title "Absorption, Pharmacokinetics, and Safety of Triclosan after Dermal Administration" @default.
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• W2160818462 doi "https://doi.org/10.1128/aac.00615-09" @default.
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