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• W2160821352 abstract "Whipple's disease is a rare cause of chronic diarrhea and abdominal pain that may be confused with inflammatory bowel disease. We report a Whipple's case misdiagnosed as Crohn's disease in which treatment with anti-tumor necrosis factor (anti-TNF) therapy led to nearly fatal progression. Lymph node tissue obtained during laparotomy for suspected bowel necrosis stained dramatically with periodic acid-Schiff (PAS), and electron microscopy showed a bacterium consistent with Trophyrema whipplei. The patient made a remarkable recovery complicated only by cholestatic hepatitis, which was likely a treatment-associated inflammatory response. This case serves as a reminder that all granulomatous infections should be considered prior to initiation of anti-TNF therapies." @default.
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• W2160821352 date "2013-10-01" @default.
• W2160821352 modified "2023-09-25" @default.
• W2160821352 title "Nearly Fatal Case of Whipple's Disease in a Patient Mistakenly on Anti-TNF Therapy" @default.
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• W2160821352 doi "https://doi.org/10.14309/crj.2013.11" @default.
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