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- W2160889646 abstract "The utilization of orotic acid for the formation of RNA ~ uracil has been extensively studied in in- tact animals, tissue slices, and cell suspensions (re- viewed in Refs. 5, 31). The mechanism of the utilization, via the initial conversion of orotic acid to uridine nucleotides and the incorporation of uri- dine nucleotides into polynucleotides, has been partially described in intact animals (13, 17) and studied in detail in enzyme systems of microbial, avian, and mammalian origin (18, 36) (reviewed in Refs. 33, 38, 39). The concomitant conversion of orotic acid to RNA cytosine has usually been observed in intact cell systems," @default.
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- W2160889646 date "1959-07-01" @default.
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- W2160889646 title "The formation of cytidine nucleotides and RNA cytosine from orotic acid by the Novikoff tumor in vitro." @default.
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