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• W2160949062 abstract "Much evidence now attests to the importance of desmosomes and their constituents in cancer. Alterations in the expression of desmosomal components could contribute to the progression of the disease by modifying intracellular signal transduction pathways and/or by causing reduced cell adhesion. The Wnt/β-catenin pathway is a potential target because of the involvement of the cytoplasmic desmosomal protein plakoglobin. Loss of desmosomal adhesion is a prerequisite for the epithelial–mesenchymal transition, implicated in the conversion of early stage tumours to invasive cancers." @default.
• W2160949062 created "2016-06-24" @default.
• W2160949062 creator A5060490985 @default.
• W2160949062 creator A5091006592 @default.
• W2160949062 date "2007-05-22" @default.
• W2160949062 modified "2023-10-10" @default.
• W2160949062 title "Desmosomes: a role in cancer?" @default.
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• W2160949062 doi "https://doi.org/10.1038/sj.bjc.6603808" @default.
• W2160949062 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2359958" @default.
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