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• W2160992834 abstract "In order to image noninvasively cell nuclei in vivo without staining, we have developed ultraviolet photoacoustic microscopy (UV-PAM), in which ultraviolet light excites nucleic acids in cell nuclei to produce photoacoustic waves. Equipped with a tunable laser system, the UV-PAM was applied to in vivo imaging of cell nuclei in small animals. We found that 250 nm was the optimal wavelength for in vivo photoacoustic imaging of cell nuclei. The optimal wavelength enables UV-PAM to image cell nuclei using as little as 2 nJ laser pulse energy. Besides the optimal wavelength, application of a wavelength between 245 and 275 nm can produce in vivo images of cell nuclei with specific, positive, and high optical contrast." @default.
• W2160992834 created "2016-06-24" @default.
• W2160992834 creator A5065654528 @default.
• W2160992834 date "2012-05-04" @default.
• W2160992834 modified "2023-10-14" @default.
• W2160992834 title "Optimal ultraviolet wavelength for <italic>in vivo</italic> photoacoustic imaging of cell nuclei" @default.
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• W2160992834 doi "https://doi.org/10.1117/1.jbo.17.5.056004" @default.
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