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- W2160997846 abstract "The impact of creatinine clearance (CrCl) in patients with cardiac resynchronization therapy (CRT) has not been well established. We investigated the ability of CrCl in patient selection for CRT in 136 patients on CRT. The CrCl was computed using Modification of Diet in Renal Disease (MDRD) equations. A decrease of left ventricular end systolic volume ≥15% after CRT was defined as a positive response to CRT. Mean CrCl level at baseline was 56.4 ± 21.1 ml/min/1.73m2. CrCl at baseline in patients who died was significantly lower than those who survived (p= 0.0007). The area under Receiver Operating Characteristic curve for CrCl predicting death was 0.73 (p= 0.0001). The cutoff point was ≤ 42 ml/min/1.73m2. During follow -up of 17.2± 9.7 months, the cardiac mortality in patients with CrCl ≤ the cutoff point was significantly higher than CrCl > cutoff point (39% versus 7%, p 42 ml/min/1.73m2. However, the ability of CrCl to predict CRT response is limited." @default.
- W2160997846 created "2016-06-24" @default.
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- W2160997846 date "2010-06-17" @default.
- W2160997846 modified "2023-09-24" @default.
- W2160997846 title "Role of Renal Function in Patient Selection For Cardiac Resynchronization Therapy" @default.
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