Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161006919> ?p ?o ?g. }
- W2161006919 endingPage "50" @default.
- W2161006919 startingPage "42" @default.
- W2161006919 abstract "A phospholipase inhibitor (WSG) has been purified from Withania somnifera using gel-filtration and ion-exchange chromatographies. The WSG is an acidic glycoprotein. Its molecular mass as determined by SDS–PAGE was 27 kDa. It neutralized the enzyme activity and pharmacological properties such as cytotoxicity, edema, and myotoxicity of a multi-toxic Indian cobra venom phospholipase (NNXIa–PLA) but failed to neutralize the neurotoxicity. The glycan part of the molecule does not appear to be involved in any of the pharmacological properties studied. The results suggest that the neutralization of the pharmacological effects of the toxic phospholipase is brought about by inhibition of the enzyme activity by formation of a complex between the WSG and the toxic phospholipase. We report the purification and characterization of a glycoprotein phospholipase A inhibitor from Withania somnifera, medicinal plant." @default.
- W2161006919 created "2016-06-24" @default.
- W2161006919 creator A5074255326 @default.
- W2161006919 creator A5083489451 @default.
- W2161006919 date "2002-12-01" @default.
- W2161006919 modified "2023-10-15" @default.
- W2161006919 title "Purification and characterization of a glycoprotein inhibitor of toxic phospholipase from Withania somnifera" @default.
- W2161006919 cites W1482693857 @default.
- W2161006919 cites W1506838377 @default.
- W2161006919 cites W1750773183 @default.
- W2161006919 cites W1775749144 @default.
- W2161006919 cites W1865154010 @default.
- W2161006919 cites W1963506876 @default.
- W2161006919 cites W1964748161 @default.
- W2161006919 cites W1968834637 @default.
- W2161006919 cites W1973285110 @default.
- W2161006919 cites W1974638548 @default.
- W2161006919 cites W1976657679 @default.
- W2161006919 cites W1983648948 @default.
- W2161006919 cites W1996146047 @default.
- W2161006919 cites W1996192007 @default.
- W2161006919 cites W1997940643 @default.
- W2161006919 cites W2003965519 @default.
- W2161006919 cites W2004494956 @default.
- W2161006919 cites W2006017537 @default.
- W2161006919 cites W2006059562 @default.
- W2161006919 cites W2010043559 @default.
- W2161006919 cites W2011469832 @default.
- W2161006919 cites W2029250606 @default.
- W2161006919 cites W2032588094 @default.
- W2161006919 cites W2039580339 @default.
- W2161006919 cites W2045090464 @default.
- W2161006919 cites W2046539321 @default.
- W2161006919 cites W2046824380 @default.
- W2161006919 cites W2050080364 @default.
- W2161006919 cites W2055227695 @default.
- W2161006919 cites W2055718795 @default.
- W2161006919 cites W2056064408 @default.
- W2161006919 cites W2058664321 @default.
- W2161006919 cites W2064915107 @default.
- W2161006919 cites W2071807502 @default.
- W2161006919 cites W2075438166 @default.
- W2161006919 cites W2077065351 @default.
- W2161006919 cites W2077815567 @default.
- W2161006919 cites W2082552678 @default.
- W2161006919 cites W2093530882 @default.
- W2161006919 cites W2100837269 @default.
- W2161006919 cites W2106592511 @default.
- W2161006919 cites W2111301002 @default.
- W2161006919 cites W2130000366 @default.
- W2161006919 cites W2143281736 @default.
- W2161006919 cites W2164931507 @default.
- W2161006919 cites W2255143444 @default.
- W2161006919 cites W2320607408 @default.
- W2161006919 cites W2416719963 @default.
- W2161006919 doi "https://doi.org/10.1016/s0003-9861(02)00527-1" @default.
- W2161006919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12485601" @default.
- W2161006919 hasPublicationYear "2002" @default.
- W2161006919 type Work @default.
- W2161006919 sameAs 2161006919 @default.
- W2161006919 citedByCount "34" @default.
- W2161006919 countsByYear W21610069192012 @default.
- W2161006919 countsByYear W21610069192013 @default.
- W2161006919 countsByYear W21610069192014 @default.
- W2161006919 countsByYear W21610069192015 @default.
- W2161006919 countsByYear W21610069192016 @default.
- W2161006919 countsByYear W21610069192017 @default.
- W2161006919 countsByYear W21610069192019 @default.
- W2161006919 countsByYear W21610069192020 @default.
- W2161006919 countsByYear W21610069192021 @default.
- W2161006919 countsByYear W21610069192022 @default.
- W2161006919 countsByYear W21610069192023 @default.
- W2161006919 crossrefType "journal-article" @default.
- W2161006919 hasAuthorship W2161006919A5074255326 @default.
- W2161006919 hasAuthorship W2161006919A5083489451 @default.
- W2161006919 hasConcept C108625454 @default.
- W2161006919 hasConcept C109316439 @default.
- W2161006919 hasConcept C12927208 @default.
- W2161006919 hasConcept C142724271 @default.
- W2161006919 hasConcept C181199279 @default.
- W2161006919 hasConcept C185592680 @default.
- W2161006919 hasConcept C202751555 @default.
- W2161006919 hasConcept C204787440 @default.
- W2161006919 hasConcept C2776551241 @default.
- W2161006919 hasConcept C2776888444 @default.
- W2161006919 hasConcept C2778597717 @default.
- W2161006919 hasConcept C2780069950 @default.
- W2161006919 hasConcept C55493867 @default.
- W2161006919 hasConcept C58121356 @default.
- W2161006919 hasConcept C71924100 @default.
- W2161006919 hasConceptScore W2161006919C108625454 @default.
- W2161006919 hasConceptScore W2161006919C109316439 @default.
- W2161006919 hasConceptScore W2161006919C12927208 @default.
- W2161006919 hasConceptScore W2161006919C142724271 @default.
- W2161006919 hasConceptScore W2161006919C181199279 @default.
- W2161006919 hasConceptScore W2161006919C185592680 @default.
- W2161006919 hasConceptScore W2161006919C202751555 @default.
- W2161006919 hasConceptScore W2161006919C204787440 @default.