FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161017029> ?p ?o ?g. }

• W2161017029 abstract "Abstract Background Understanding co-receptor tropism of HIV-1 strains circulating in India will provide key analytical leverage for assessing the potential usefulness of newer antiretroviral drugs such as chemokine co-receptor antagonists among Indian HIV-infected populations. The objective of this study was to determine using in silico methods, HIV-1 tropism among a large number of Indian isolates both from primary clinical isolates as well as from database-derived sequences. Results R5-tropism was seen in 96.8% of a total of 1045 HIV-1 subtype C Indian sequences. Co-receptor prediction of 15 primary clinical isolates detected two X4-tropic strains using the C-PSSM matrix. R5-tropic HIV-1 subtype C V3 sequences were conserved to a greater extent than X4-tropic strains. X4-tropic strains were obtained from subjects who had a significantly longer time since HIV diagnosis (96.5 months) compared to R5-tropic strains (20.5 months). Conclusions High prevalence of R5 tropism and greater homogeneity of the V3 sequence among HIV-1 subtype C strains in India suggests the potential benefit of CCR5 antagonists as a therapeutic option in India." @default.
• W2161017029 created "2016-06-24" @default.
• W2161017029 creator A5020997464 @default.
• W2161017029 creator A5021206936 @default.
• W2161017029 creator A5030957826 @default.
• W2161017029 creator A5043880711 @default.
• W2161017029 creator A5053300883 @default.
• W2161017029 creator A5067701679 @default.
• W2161017029 creator A5081889039 @default.
• W2161017029 date "2010-07-21" @default.
• W2161017029 modified "2023-10-17" @default.
• W2161017029 title "Co-receptor tropism prediction among 1045 Indian HIV-1 subtype C sequences: Therapeutic implications for India" @default.
• W2161017029 cites W101727076 @default.
• W2161017029 cites W1517417834 @default.
• W2161017029 cites W1963596540 @default.
• W2161017029 cites W1972939822 @default.
• W2161017029 cites W1981164507 @default.
• W2161017029 cites W1981440980 @default.
• W2161017029 cites W1989035987 @default.
• W2161017029 cites W1989091541 @default.
• W2161017029 cites W1995198826 @default.
• W2161017029 cites W2005285871 @default.
• W2161017029 cites W2012356776 @default.
• W2161017029 cites W2039825890 @default.
• W2161017029 cites W2044874413 @default.
• W2161017029 cites W2076666663 @default.
• W2161017029 cites W2087364590 @default.
• W2161017029 cites W2090826477 @default.
• W2161017029 cites W2101247921 @default.
• W2161017029 cites W2112097111 @default.
• W2161017029 cites W2113282092 @default.
• W2161017029 cites W2127428890 @default.
• W2161017029 cites W2151200015 @default.
• W2161017029 cites W2157438507 @default.
• W2161017029 cites W2157833154 @default.
• W2161017029 cites W2163431297 @default.
• W2161017029 cites W2163551936 @default.
• W2161017029 cites W2164056759 @default.
• W2161017029 cites W2172148966 @default.
• W2161017029 doi "https://doi.org/10.1186/1742-6405-7-24" @default.
• W2161017029 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2918521" @default.
• W2161017029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20646329" @default.
• W2161017029 hasPublicationYear "2010" @default.
• W2161017029 type Work @default.
• W2161017029 sameAs 2161017029 @default.
• W2161017029 citedByCount "14" @default.
• W2161017029 countsByYear W21610170292012 @default.
• W2161017029 countsByYear W21610170292013 @default.
• W2161017029 countsByYear W21610170292014 @default.
• W2161017029 countsByYear W21610170292015 @default.
• W2161017029 countsByYear W21610170292017 @default.
• W2161017029 countsByYear W21610170292020 @default.
• W2161017029 crossrefType "journal-article" @default.
• W2161017029 hasAuthorship W2161017029A5020997464 @default.
• W2161017029 hasAuthorship W2161017029A5021206936 @default.
• W2161017029 hasAuthorship W2161017029A5030957826 @default.
• W2161017029 hasAuthorship W2161017029A5043880711 @default.
• W2161017029 hasAuthorship W2161017029A5053300883 @default.
• W2161017029 hasAuthorship W2161017029A5067701679 @default.
• W2161017029 hasAuthorship W2161017029A5081889039 @default.
• W2161017029 hasBestOaLocation W21610170291 @default.
• W2161017029 hasConcept C104317684 @default.
• W2161017029 hasConcept C125590012 @default.
• W2161017029 hasConcept C126322002 @default.
• W2161017029 hasConcept C12823836 @default.
• W2161017029 hasConcept C13373296 @default.
• W2161017029 hasConcept C159047783 @default.
• W2161017029 hasConcept C170493617 @default.
• W2161017029 hasConcept C2522874641 @default.
• W2161017029 hasConcept C2775905019 @default.
• W2161017029 hasConcept C3013748606 @default.
• W2161017029 hasConcept C33602714 @default.
• W2161017029 hasConcept C35693153 @default.
• W2161017029 hasConcept C37044404 @default.
• W2161017029 hasConcept C54355233 @default.
• W2161017029 hasConcept C71924100 @default.
• W2161017029 hasConcept C86803240 @default.
• W2161017029 hasConceptScore W2161017029C104317684 @default.
• W2161017029 hasConceptScore W2161017029C125590012 @default.
• W2161017029 hasConceptScore W2161017029C126322002 @default.
• W2161017029 hasConceptScore W2161017029C12823836 @default.
• W2161017029 hasConceptScore W2161017029C13373296 @default.
• W2161017029 hasConceptScore W2161017029C159047783 @default.
• W2161017029 hasConceptScore W2161017029C170493617 @default.
• W2161017029 hasConceptScore W2161017029C2522874641 @default.
• W2161017029 hasConceptScore W2161017029C2775905019 @default.
• W2161017029 hasConceptScore W2161017029C3013748606 @default.
• W2161017029 hasConceptScore W2161017029C33602714 @default.
• W2161017029 hasConceptScore W2161017029C35693153 @default.
• W2161017029 hasConceptScore W2161017029C37044404 @default.
• W2161017029 hasConceptScore W2161017029C54355233 @default.
• W2161017029 hasConceptScore W2161017029C71924100 @default.
• W2161017029 hasConceptScore W2161017029C86803240 @default.
• W2161017029 hasIssue "1" @default.
• W2161017029 hasLocation W21610170291 @default.
• W2161017029 hasLocation W21610170292 @default.
• W2161017029 hasLocation W21610170293 @default.
• W2161017029 hasLocation W21610170294 @default.
• W2161017029 hasOpenAccess W2161017029 @default.
• W2161017029 hasPrimaryLocation W21610170291 @default.

• next