Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161050147> ?p ?o ?g. }
- W2161050147 endingPage "429" @default.
- W2161050147 startingPage "423" @default.
- W2161050147 abstract "We investigated the association among plasma levels of oxidatively modified low-density lipoprotein (Ox-LDL), high-density lipoprotein-cholesterol (HDL-C), and the prevalence of coronary artery disease (CAD) in a case-control study. Cases (n = 183, male [M]/female [F]:138/45, age: 64.9 ± 10.6 years) were defined as patients with angiographically proven coronary atherosclerosis (≥50% stenosis) and controls were subjects with normal coronary arteries (n = 74, M/F:36/38, age: 57.6 ± 14.4 years). Plasma Ox-LDL levels were measured by a sensitive detection method using the monoclonal antibody DLH3. In women, both Ox-LDL and lipid variables were similar between cases and controls. In men, cases had significantly lower (P < .05) levels of HDL-C (39.1 ± 10.3 v 42.8 ± 10.9 mg/dL) and apolipoprotein (apo) A-I than controls, while the difference in Ox-LDL between cases and controls was not significant (1.05 ± 0.79 and 0.83 ± 0.65 ng/10 μg LDL protein, respectively). However, HDL-C levels interacted with the association between Ox-LDL levels and CAD in males: increased Ox-LDL levels were significantly associated with CAD after controlling for age when HDL-C levels were high, but were not associated with CAD when HDL-C levels were low, as assessed by a multiple logistic regression analysis. In addition, the combination of HDL-C and Ox-LDL levels was a better indicator for CAD in males than HDL-C levels alone (−2 log likelihood, 24.1 v 19.4) after controlling for age and conventional risk factors of CAD, while Ox-LDL levels were not significantly associated with CAD. HDL-C levels interact with the association between plasma Ox-LDL levels and CAD in men, and increased Ox-LDL levels are an indicator of CAD in male subjects with high HDL-C levels." @default.
- W2161050147 created "2016-06-24" @default.
- W2161050147 creator A5004090521 @default.
- W2161050147 creator A5011877804 @default.
- W2161050147 creator A5055255364 @default.
- W2161050147 creator A5062121150 @default.
- W2161050147 creator A5081255637 @default.
- W2161050147 creator A5081586028 @default.
- W2161050147 creator A5081675173 @default.
- W2161050147 date "2004-04-01" @default.
- W2161050147 modified "2023-10-17" @default.
- W2161050147 title "Serum high-density lipoprotein-cholesterol levels modify the association between plasma levels of oxidatively modified low-density lipoprotein and coronary artery disease in men" @default.
- W2161050147 cites W1487930529 @default.
- W2161050147 cites W1671050155 @default.
- W2161050147 cites W1899782582 @default.
- W2161050147 cites W1911084134 @default.
- W2161050147 cites W1970984181 @default.
- W2161050147 cites W1974078432 @default.
- W2161050147 cites W1992085688 @default.
- W2161050147 cites W2001047636 @default.
- W2161050147 cites W2003671495 @default.
- W2161050147 cites W2007085863 @default.
- W2161050147 cites W2022016504 @default.
- W2161050147 cites W2045670005 @default.
- W2161050147 cites W2046305388 @default.
- W2161050147 cites W2046834178 @default.
- W2161050147 cites W2051170697 @default.
- W2161050147 cites W2056211385 @default.
- W2161050147 cites W2064455581 @default.
- W2161050147 cites W2064861744 @default.
- W2161050147 cites W2077760013 @default.
- W2161050147 cites W2088551005 @default.
- W2161050147 cites W2092176760 @default.
- W2161050147 cites W2122115743 @default.
- W2161050147 cites W2125387769 @default.
- W2161050147 cites W2135503869 @default.
- W2161050147 cites W2136976666 @default.
- W2161050147 cites W2144302240 @default.
- W2161050147 cites W2149762754 @default.
- W2161050147 cites W2154529111 @default.
- W2161050147 cites W2156754250 @default.
- W2161050147 cites W2159968187 @default.
- W2161050147 cites W2171416452 @default.
- W2161050147 cites W2330503938 @default.
- W2161050147 cites W2339616051 @default.
- W2161050147 cites W2473564715 @default.
- W2161050147 cites W4245484764 @default.
- W2161050147 doi "https://doi.org/10.1016/j.metabol.2003.10.028" @default.
- W2161050147 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15045686" @default.
- W2161050147 hasPublicationYear "2004" @default.
- W2161050147 type Work @default.
- W2161050147 sameAs 2161050147 @default.
- W2161050147 citedByCount "12" @default.
- W2161050147 countsByYear W21610501472013 @default.
- W2161050147 countsByYear W21610501472014 @default.
- W2161050147 countsByYear W21610501472016 @default.
- W2161050147 crossrefType "journal-article" @default.
- W2161050147 hasAuthorship W2161050147A5004090521 @default.
- W2161050147 hasAuthorship W2161050147A5011877804 @default.
- W2161050147 hasAuthorship W2161050147A5055255364 @default.
- W2161050147 hasAuthorship W2161050147A5062121150 @default.
- W2161050147 hasAuthorship W2161050147A5081255637 @default.
- W2161050147 hasAuthorship W2161050147A5081586028 @default.
- W2161050147 hasAuthorship W2161050147A5081675173 @default.
- W2161050147 hasConcept C126322002 @default.
- W2161050147 hasConcept C134018914 @default.
- W2161050147 hasConcept C151956035 @default.
- W2161050147 hasConcept C2776104379 @default.
- W2161050147 hasConcept C2778163477 @default.
- W2161050147 hasConcept C2778213512 @default.
- W2161050147 hasConcept C2779620165 @default.
- W2161050147 hasConcept C2780072125 @default.
- W2161050147 hasConcept C2780541478 @default.
- W2161050147 hasConcept C62746215 @default.
- W2161050147 hasConcept C71924100 @default.
- W2161050147 hasConceptScore W2161050147C126322002 @default.
- W2161050147 hasConceptScore W2161050147C134018914 @default.
- W2161050147 hasConceptScore W2161050147C151956035 @default.
- W2161050147 hasConceptScore W2161050147C2776104379 @default.
- W2161050147 hasConceptScore W2161050147C2778163477 @default.
- W2161050147 hasConceptScore W2161050147C2778213512 @default.
- W2161050147 hasConceptScore W2161050147C2779620165 @default.
- W2161050147 hasConceptScore W2161050147C2780072125 @default.
- W2161050147 hasConceptScore W2161050147C2780541478 @default.
- W2161050147 hasConceptScore W2161050147C62746215 @default.
- W2161050147 hasConceptScore W2161050147C71924100 @default.
- W2161050147 hasFunder F4320310760 @default.
- W2161050147 hasFunder F4320320912 @default.
- W2161050147 hasFunder F4320322034 @default.
- W2161050147 hasFunder F4320335046 @default.
- W2161050147 hasIssue "4" @default.
- W2161050147 hasLocation W21610501471 @default.
- W2161050147 hasLocation W21610501472 @default.
- W2161050147 hasOpenAccess W2161050147 @default.
- W2161050147 hasPrimaryLocation W21610501471 @default.
- W2161050147 hasRelatedWork W1558566237 @default.
- W2161050147 hasRelatedWork W1633796242 @default.
- W2161050147 hasRelatedWork W1968470393 @default.