FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161123669> ?p ?o ?g. }

• W2161123669 endingPage "103" @default.
• W2161123669 startingPage "97" @default.
• W2161123669 abstract "cDNA representational difference analysis (cDNA-RDA) is a polymerase-chain-reaction-coupled subtractive and kinetic enrichment procedure for the isolation of differentially expressed genes. In this study, the technique was used to isolate novel genes specifically expressed in pancreatic cancer. cDNA-RDA was done on cDNA reverse transcribed from a poly(A)+ mRNA pool made from 10 cancer tissues (tester) by using as a driver a cDNA from a poly(A)+ mRNA pool made from a combination of 10 tissues of chronic pancreatitis and 10 healthy pancreatic tissues. The use of chronic pancreatitis in addition to healthy pancreas mRNA in the driver preparation eliminated the influence of stromal tissue components present as contamination in the cancer-specific preparations. Such cDNA-RDA led to the isolation of 16 distinct, cancer-specific gene fragments. These were confirmed to be overexpressed in pancreatic cancer tissues by Northern blot analysis. Sequence analysis revealed homologies to five genes previously implicated in the carcinogenesis of the pancreas or other tissues. Eleven fragments had no significant homology to any known gene and thus represent novel candidate disease genes. The experiments demonstrate that cDNA-RDA is a reproducible and highly efficient method for the identification of novel genes with cancer-specific expression. Genes Chromosom. Cancer 19:97–103, 1997. © 1997 Wiley-Liss, Inc." @default.
• W2161123669 created "2016-06-24" @default.
• W2161123669 creator A5005961081 @default.
• W2161123669 creator A5005985824 @default.
• W2161123669 creator A5017815858 @default.
• W2161123669 creator A5026608305 @default.
• W2161123669 creator A5036032282 @default.
• W2161123669 creator A5047168458 @default.
• W2161123669 creator A5048928035 @default.
• W2161123669 creator A5067780549 @default.
• W2161123669 creator A5080497221 @default.
• W2161123669 date "1997-06-01" @default.
• W2161123669 modified "2023-09-23" @default.
• W2161123669 title "Identification of genes with specific expression in pancreatic cancer by cDNA representational difference analysis" @default.
• W2161123669 cites W137347384 @default.
• W2161123669 cites W1968964998 @default.
• W2161123669 cites W1978368163 @default.
• W2161123669 cites W1979366210 @default.
• W2161123669 cites W2001458398 @default.
• W2161123669 cites W2004625262 @default.
• W2161123669 cites W2005453259 @default.
• W2161123669 cites W2012684443 @default.
• W2161123669 cites W2021625932 @default.
• W2161123669 cites W2027590165 @default.
• W2161123669 cites W2031725843 @default.
• W2161123669 cites W2034831308 @default.
• W2161123669 cites W2037482201 @default.
• W2161123669 cites W2055043387 @default.
• W2161123669 cites W2065887922 @default.
• W2161123669 cites W2080979909 @default.
• W2161123669 cites W2096081784 @default.
• W2161123669 cites W2101455212 @default.
• W2161123669 cites W2165539456 @default.
• W2161123669 cites W3188033896 @default.
• W2161123669 doi "https://doi.org/10.1002/(sici)1098-2264(199706)19:2<97::aid-gcc5>3.0.co;2-v" @default.
• W2161123669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9172000" @default.
• W2161123669 hasPublicationYear "1997" @default.
• W2161123669 type Work @default.
• W2161123669 sameAs 2161123669 @default.
• W2161123669 citedByCount "63" @default.
• W2161123669 countsByYear W21611236692012 @default.
• W2161123669 countsByYear W21611236692014 @default.
• W2161123669 countsByYear W21611236692015 @default.
• W2161123669 countsByYear W21611236692017 @default.
• W2161123669 countsByYear W21611236692019 @default.
• W2161123669 countsByYear W21611236692020 @default.
• W2161123669 crossrefType "journal-article" @default.
• W2161123669 hasAuthorship W2161123669A5005961081 @default.
• W2161123669 hasAuthorship W2161123669A5005985824 @default.
• W2161123669 hasAuthorship W2161123669A5017815858 @default.
• W2161123669 hasAuthorship W2161123669A5026608305 @default.
• W2161123669 hasAuthorship W2161123669A5036032282 @default.
• W2161123669 hasAuthorship W2161123669A5047168458 @default.
• W2161123669 hasAuthorship W2161123669A5048928035 @default.
• W2161123669 hasAuthorship W2161123669A5067780549 @default.
• W2161123669 hasAuthorship W2161123669A5080497221 @default.
• W2161123669 hasConcept C104317684 @default.
• W2161123669 hasConcept C121608353 @default.
• W2161123669 hasConcept C149034497 @default.
• W2161123669 hasConcept C150194340 @default.
• W2161123669 hasConcept C153911025 @default.
• W2161123669 hasConcept C177707886 @default.
• W2161123669 hasConcept C187882448 @default.
• W2161123669 hasConcept C189482833 @default.
• W2161123669 hasConcept C196436469 @default.
• W2161123669 hasConcept C19924922 @default.
• W2161123669 hasConcept C2779372761 @default.
• W2161123669 hasConcept C2780210213 @default.
• W2161123669 hasConcept C50724178 @default.
• W2161123669 hasConcept C54355233 @default.
• W2161123669 hasConcept C555283112 @default.
• W2161123669 hasConcept C86803240 @default.
• W2161123669 hasConceptScore W2161123669C104317684 @default.
• W2161123669 hasConceptScore W2161123669C121608353 @default.
• W2161123669 hasConceptScore W2161123669C149034497 @default.
• W2161123669 hasConceptScore W2161123669C150194340 @default.
• W2161123669 hasConceptScore W2161123669C153911025 @default.
• W2161123669 hasConceptScore W2161123669C177707886 @default.
• W2161123669 hasConceptScore W2161123669C187882448 @default.
• W2161123669 hasConceptScore W2161123669C189482833 @default.
• W2161123669 hasConceptScore W2161123669C196436469 @default.
• W2161123669 hasConceptScore W2161123669C19924922 @default.
• W2161123669 hasConceptScore W2161123669C2779372761 @default.
• W2161123669 hasConceptScore W2161123669C2780210213 @default.
• W2161123669 hasConceptScore W2161123669C50724178 @default.
• W2161123669 hasConceptScore W2161123669C54355233 @default.
• W2161123669 hasConceptScore W2161123669C555283112 @default.
• W2161123669 hasConceptScore W2161123669C86803240 @default.
• W2161123669 hasIssue "2" @default.
• W2161123669 hasLocation W21611236691 @default.
• W2161123669 hasLocation W21611236692 @default.
• W2161123669 hasOpenAccess W2161123669 @default.
• W2161123669 hasPrimaryLocation W21611236691 @default.
• W2161123669 hasRelatedWork W1531528770 @default.
• W2161123669 hasRelatedWork W2161123669 @default.
• W2161123669 hasRelatedWork W2163567654 @default.
• W2161123669 hasRelatedWork W2353496559 @default.
• W2161123669 hasRelatedWork W2382593249 @default.

• next