FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161198266> ?p ?o ?g. }

• W2161198266 endingPage "1061" @default.
• W2161198266 startingPage "1050" @default.
• W2161198266 abstract "Factors accelerating cerebral degenerative changes represent potentially modifiable risks for cognitive decline. Putative risk factors accelerating subtle cognitive decline and dementia were correlated with repeated measures of cerebral atrophy, CT densitometry, perfusions and cognitive testing among neurologically and cognitively normative ageing volunteers.Two hundred and twenty-four normative subjects at increased risk for cognitive decline were admitted to the study. Mean entry age was 59. 5+/-15.8 years. Mean follow-up is 4.3+/-3.1 years. At follow-up, 22 developed subtle cognitive decline (deltaCCSE>/=-3), 19 became demented, eight with vascular type (VAD) and 11 with Alzheimer's type (DAT) and 183 remain cognitively unchanged. Standardized questionnaires, medical, neuropsychological, neurological and blood work examinations were obtained. Cerebral atrophy, tissue densities and perfusions were measured by xenon-enhanced CT.After age 60, cerebral atrophy, ventricular enlargement, polio- and leuko-araiosis geometrically increased as perfusions declined. Risk factors accelerating perfusional decline, cerebral atrophy, polio-araiosis and leuko-araiosis (thinning of grey-white matter densities) were: transient ischaemic attacks (TIAs), hypertension, smoking, hyperlipidemia, male gender. At age 71.5+/-11.9, subtle cognitive decline began, accelerated by TIAs, hypertension and heart disease. Leuko-araiosis began before cognitive decline. TIAs, hypertension and hyperlipidemia correlated with VAD. Excessive cortical perfusional decreases and cerebral atrophy correlated with cognitive decline. Family history of neurodegenerative disease correlated with DAT.TIAs, hypertension, hyperlipidemia, smoking and male gender accelerate cerebral degenerative changes, cognitive decline and dementia." @default.
• W2161198266 created "2016-06-24" @default.
• W2161198266 creator A5010556108 @default.
• W2161198266 creator A5018536550 @default.
• W2161198266 creator A5026134236 @default.
• W2161198266 creator A5030503300 @default.
• W2161198266 creator A5033954307 @default.
• W2161198266 creator A5047956563 @default.
• W2161198266 creator A5050156974 @default.
• W2161198266 creator A5089253647 @default.
• W2161198266 date "1999-12-01" @default.
• W2161198266 modified "2023-09-24" @default.
• W2161198266 title "Risk factors accelerating cerebral degenerative changes, cognitive decline and dementia" @default.
• W2161198266 cites W1494700569 @default.
• W2161198266 cites W1594448327 @default.
• W2161198266 cites W1847168837 @default.
• W2161198266 cites W1968401437 @default.
• W2161198266 cites W1970331216 @default.
• W2161198266 cites W1971484632 @default.
• W2161198266 cites W1971914736 @default.
• W2161198266 cites W1973346209 @default.
• W2161198266 cites W1985228761 @default.
• W2161198266 cites W1988376844 @default.
• W2161198266 cites W1990866341 @default.
• W2161198266 cites W1994118653 @default.
• W2161198266 cites W1999128075 @default.
• W2161198266 cites W2000790999 @default.
• W2161198266 cites W2004311396 @default.
• W2161198266 cites W2005810979 @default.
• W2161198266 cites W2006102164 @default.
• W2161198266 cites W2006548053 @default.
• W2161198266 cites W2012275755 @default.
• W2161198266 cites W2015734662 @default.
• W2161198266 cites W2016801911 @default.
• W2161198266 cites W2022394206 @default.
• W2161198266 cites W2036228385 @default.
• W2161198266 cites W2043447152 @default.
• W2161198266 cites W2050209993 @default.
• W2161198266 cites W2050849358 @default.
• W2161198266 cites W2051675065 @default.
• W2161198266 cites W2057638542 @default.
• W2161198266 cites W2069557161 @default.
• W2161198266 cites W2070896524 @default.
• W2161198266 cites W2073101750 @default.
• W2161198266 cites W2081841031 @default.
• W2161198266 cites W2081903011 @default.
• W2161198266 cites W2083579475 @default.
• W2161198266 cites W2087959325 @default.
• W2161198266 cites W2089390439 @default.
• W2161198266 cites W2091720658 @default.
• W2161198266 cites W2094464866 @default.
• W2161198266 cites W2117199861 @default.
• W2161198266 cites W2124381540 @default.
• W2161198266 cites W2134532614 @default.
• W2161198266 cites W2142901667 @default.
• W2161198266 cites W2147429847 @default.
• W2161198266 cites W2147432775 @default.
• W2161198266 cites W2152907424 @default.
• W2161198266 cites W2159588182 @default.
• W2161198266 cites W2168926185 @default.
• W2161198266 cites W4211045864 @default.
• W2161198266 cites W4240347348 @default.
• W2161198266 doi "https://doi.org/10.1002/(sici)1099-1166(199912)14:12<1050::aid-gps56>3.0.co;2-z" @default.
• W2161198266 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10607973" @default.
• W2161198266 hasPublicationYear "1999" @default.
• W2161198266 type Work @default.
• W2161198266 sameAs 2161198266 @default.
• W2161198266 citedByCount "126" @default.
• W2161198266 countsByYear W21611982662012 @default.
• W2161198266 countsByYear W21611982662013 @default.
• W2161198266 countsByYear W21611982662014 @default.
• W2161198266 countsByYear W21611982662015 @default.
• W2161198266 countsByYear W21611982662016 @default.
• W2161198266 countsByYear W21611982662018 @default.
• W2161198266 countsByYear W21611982662019 @default.
• W2161198266 countsByYear W21611982662020 @default.
• W2161198266 countsByYear W21611982662021 @default.
• W2161198266 countsByYear W21611982662022 @default.
• W2161198266 countsByYear W21611982662023 @default.
• W2161198266 crossrefType "journal-article" @default.
• W2161198266 hasAuthorship W2161198266A5010556108 @default.
• W2161198266 hasAuthorship W2161198266A5018536550 @default.
• W2161198266 hasAuthorship W2161198266A5026134236 @default.
• W2161198266 hasAuthorship W2161198266A5030503300 @default.
• W2161198266 hasAuthorship W2161198266A5033954307 @default.
• W2161198266 hasAuthorship W2161198266A5047956563 @default.
• W2161198266 hasAuthorship W2161198266A5050156974 @default.
• W2161198266 hasAuthorship W2161198266A5089253647 @default.
• W2161198266 hasConcept C126322002 @default.
• W2161198266 hasConcept C126838900 @default.
• W2161198266 hasConcept C134018914 @default.
• W2161198266 hasConcept C143409427 @default.
• W2161198266 hasConcept C146638467 @default.
• W2161198266 hasConcept C15744967 @default.
• W2161198266 hasConcept C164705383 @default.
• W2161198266 hasConcept C2779091943 @default.
• W2161198266 hasConcept C2779134260 @default.
• W2161198266 hasConcept C2779483572 @default.

• next