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- W2161237560 abstract "REPORT OF A CASE A 16-year-old African American girl presented with several asymptomatic cutaneous lesions on her chest that she said arose within chickenpox scars. Examination revealed several dome-shaped, firm, flesh-colored papules and nodules ranging from 4 to 10 mm in diameter. The overlying epidermis was intact without crusting or scale ( Figure 1 ). The remainder of the skin examination showed scattered varicella scars. The results of laboratory investigations, including a complete blood cell count, erythrocyte sedimentation rate, immunologic studies, and serum protein electrophoresis, were unremarkable. A chest x-ray film and an abdominal computed tomogram were normal. A biopsy specimen was obtained for routine histopathological evaluation ( Figure 2 and Figure 3 ). S100 protein immunolabeling is illustrated in Figure 4. What is your diagnosis? DIAGNOSIS: Cutaneous sinus histiocytosis (CSH) (cutaneous Rosai-Dorfman disease). Sinus histiocytosis with massive lymphadenopathy (SHML) was first described by Rosai and Dorfman 1 in 1969. In its usual clinical presentation, this distinct entity is characterized by marked enlargement of the lymph nodes, especially those" @default.
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- W2161237560 date "1997-02-01" @default.
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- W2161237560 title "Asymptomatic Nodules on the Chest" @default.
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- W2161237560 doi "https://doi.org/10.1001/archderm.1997.03890380109020" @default.
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