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• W2161275314 abstract "We conducted serial studies on peripheral blood lymphocytes from four patients with acute Coxiella burnetii infection. These studies revealed that the proportion of ϒδ T cells in these patients significantly increased after the onset of disease (mean, 16%; range, 13%–30%) as compared with that in five healthy controls (mean, 4%; range, 0.5%–7%; P < .0055) and that in five controls with pneumonia (mean, 2%; range, 1%–3%; P < .0014). Most of the ϒδ T cells from these patients expressed the Vϒ9Vδ2 gene product. During the acute phase of disease, most ϒδ T cells expressed the activation marker human leukocyte antigen DR but not CD25. During this phase, ϒ;δ T cell activation was higher than αβ T cell activation. Our findings indicate that ϒδ T cells are predominantly involved in the acute immune response to C. burnetii." @default.
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• W2161275314 date "1997-02-01" @default.
• W2161275314 modified "2023-10-17" @default.
• W2161275314 title "The Number and Proportion of V 9V 2 T Cells Rise Significantly in the Peripheral Blood of Patients After the Onset of Acute Coxiella burnetii Infection" @default.
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• W2161275314 doi "https://doi.org/10.1093/clinids/24.2.261" @default.
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