Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161315768> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2161315768 endingPage "29" @default.
- W2161315768 startingPage "23" @default.
- W2161315768 abstract "Dyslipidemia in diabetes mellitus is a significant risk factor for the development of cardiovascular complications. The aim of this study was to evaluate the effect of the ethyl-acetate fraction of an ethanolic extract from Streospermum suaveolens on lipid metabolism in streptozotocin (STZ)-induced diabetic rats.Diabetes was induced by intraperitonial injection of STZ (50 mg/kg). Diabetic rats were treated with an ethyl-acetate fraction orally at doses of 200 and 400 mg/kg daily for 14 days. On the 15(th) day, serum lipid profiles, such as total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL), were estimated in experimental rats. The atherogenic (AI) and the coronary risk (CRI) indices were also evaluated.The ethyl-acetate fraction at doses of 200 and 400 mg/kg significantly (P< 0.001) and dose-dependently reduced serum cholesterol, triglycerides and LDL, but increased HDL towards near normal levels as compared to diabetic control rats. The fraction also significantly (P< 0.001) lowered the atherogenic index (AI) and coronary risk index (CAI) in a dose-dependent manner.The present study demonstrated that the ethyl-acetate fraction of Stereospermum suaveolens exhibits a potent antihyperlipidemic activity in hyperglycemic rats and suggests that the plant may have therapeutic value in treating the diabetic complication of hyperlipidemia." @default.
- W2161315768 created "2016-06-24" @default.
- W2161315768 creator A5045792186 @default.
- W2161315768 creator A5048166676 @default.
- W2161315768 creator A5073117592 @default.
- W2161315768 creator A5075762177 @default.
- W2161315768 date "2013-09-30" @default.
- W2161315768 modified "2023-10-14" @default.
- W2161315768 title "Antihyperlipidemic Activity of the Ethyl-acetate Fraction of Stereospermum Suaveolens in Streptozotocin-induced Diabetic Rats" @default.
- W2161315768 cites W1976191764 @default.
- W2161315768 cites W1979080082 @default.
- W2161315768 cites W1999554610 @default.
- W2161315768 cites W2001844931 @default.
- W2161315768 cites W2013529909 @default.
- W2161315768 cites W2026015192 @default.
- W2161315768 cites W2037641287 @default.
- W2161315768 cites W2045453026 @default.
- W2161315768 cites W2065210554 @default.
- W2161315768 cites W2075401586 @default.
- W2161315768 cites W2078621701 @default.
- W2161315768 cites W2079852052 @default.
- W2161315768 cites W2082995727 @default.
- W2161315768 cites W2089316490 @default.
- W2161315768 cites W2103789620 @default.
- W2161315768 cites W2129647194 @default.
- W2161315768 cites W2141757502 @default.
- W2161315768 cites W2328771515 @default.
- W2161315768 cites W2615455765 @default.
- W2161315768 cites W27914534 @default.
- W2161315768 doi "https://doi.org/10.3831/kpi.2013.16.020" @default.
- W2161315768 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4331969" @default.
- W2161315768 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25780672" @default.
- W2161315768 hasPublicationYear "2013" @default.
- W2161315768 type Work @default.
- W2161315768 sameAs 2161315768 @default.
- W2161315768 citedByCount "3" @default.
- W2161315768 countsByYear W21613157682015 @default.
- W2161315768 countsByYear W21613157682018 @default.
- W2161315768 countsByYear W21613157682023 @default.
- W2161315768 crossrefType "journal-article" @default.
- W2161315768 hasAuthorship W2161315768A5045792186 @default.
- W2161315768 hasAuthorship W2161315768A5048166676 @default.
- W2161315768 hasAuthorship W2161315768A5073117592 @default.
- W2161315768 hasAuthorship W2161315768A5075762177 @default.
- W2161315768 hasBestOaLocation W21613157681 @default.
- W2161315768 hasConcept C126322002 @default.
- W2161315768 hasConcept C134018914 @default.
- W2161315768 hasConcept C185592680 @default.
- W2161315768 hasConcept C2778096610 @default.
- W2161315768 hasConcept C2778163477 @default.
- W2161315768 hasConcept C2779091943 @default.
- W2161315768 hasConcept C2779280383 @default.
- W2161315768 hasConcept C2779858419 @default.
- W2161315768 hasConcept C2780541478 @default.
- W2161315768 hasConcept C55493867 @default.
- W2161315768 hasConcept C555293320 @default.
- W2161315768 hasConcept C556039675 @default.
- W2161315768 hasConcept C71924100 @default.
- W2161315768 hasConcept C98274493 @default.
- W2161315768 hasConceptScore W2161315768C126322002 @default.
- W2161315768 hasConceptScore W2161315768C134018914 @default.
- W2161315768 hasConceptScore W2161315768C185592680 @default.
- W2161315768 hasConceptScore W2161315768C2778096610 @default.
- W2161315768 hasConceptScore W2161315768C2778163477 @default.
- W2161315768 hasConceptScore W2161315768C2779091943 @default.
- W2161315768 hasConceptScore W2161315768C2779280383 @default.
- W2161315768 hasConceptScore W2161315768C2779858419 @default.
- W2161315768 hasConceptScore W2161315768C2780541478 @default.
- W2161315768 hasConceptScore W2161315768C55493867 @default.
- W2161315768 hasConceptScore W2161315768C555293320 @default.
- W2161315768 hasConceptScore W2161315768C556039675 @default.
- W2161315768 hasConceptScore W2161315768C71924100 @default.
- W2161315768 hasConceptScore W2161315768C98274493 @default.
- W2161315768 hasIssue "3" @default.
- W2161315768 hasLocation W21613157681 @default.
- W2161315768 hasLocation W21613157682 @default.
- W2161315768 hasLocation W21613157683 @default.
- W2161315768 hasLocation W21613157684 @default.
- W2161315768 hasOpenAccess W2161315768 @default.
- W2161315768 hasPrimaryLocation W21613157681 @default.
- W2161315768 hasRelatedWork W1995071802 @default.
- W2161315768 hasRelatedWork W2004012005 @default.
- W2161315768 hasRelatedWork W2009443436 @default.
- W2161315768 hasRelatedWork W2011709829 @default.
- W2161315768 hasRelatedWork W2055342276 @default.
- W2161315768 hasRelatedWork W2092993950 @default.
- W2161315768 hasRelatedWork W2095626059 @default.
- W2161315768 hasRelatedWork W2140892006 @default.
- W2161315768 hasRelatedWork W2158125198 @default.
- W2161315768 hasRelatedWork W2418228134 @default.
- W2161315768 hasVolume "16" @default.
- W2161315768 isParatext "false" @default.
- W2161315768 isRetracted "false" @default.
- W2161315768 magId "2161315768" @default.
- W2161315768 workType "article" @default.