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• W2161333264 abstract "The aim of this study was to determine the percentage of lymphocyte subsets in peripheral blood in patients with active tuberculosis. A total of 21 patients with active tuberculosis and 15 healthy volunteers were included in the study. T-lymphocyte subsets, B-lymphocytes (CD19 + cells), natural killer (NK) cells and cells positive for costimulatory molecules CD28 and CD152 were evaluated using flow cytometry. Patients with tuberculosis had a significantly decreased percentage of CD3 + and CD3 + CD4 + cells, and a significantly decreased ratio of CD3 + CD4 + to CD3 + CD8 + cells compared with healthy controls. In contrast, the percentage of B-cells (CD19 + cells), CD3 + CD8 + cells, CD28 + cells, CD152 + cells, and subpopulations of CD4 + CD152 + , CD8 + CD152 + and CD8 + CD28 + T-cells were all significantly increased compared with healthy controls. There were no statistically significant differences in the percentages of NK cells or CD4 + CD28 + cells between patients and controls. These results indicate that patients with active tuberculosis have altered lymphocyte homeostasis." @default.
• W2161333264 created "2016-06-24" @default.
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• W2161333264 date "2009-12-01" @default.
• W2161333264 modified "2023-10-13" @default.
• W2161333264 title "Changes in Lymphocyte Subsets in the Peripheral Blood of Patients with Active Pulmonary Tuberculosis" @default.
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• W2161333264 doi "https://doi.org/10.1177/147323000903700610" @default.
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