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• W2161405511 abstract "Investigations regarding association of MTHFR polymorphisms with oral carcinoma risk have yielded inconclusive results. Thus, meta-analyses were performed. Results showed that no associations of C677T polymorphisms with oral carcinoma were observed for the overall data. In subgroup analyses by drinking status, homozygous TT alleles exhibited elevated oral cancer susceptibility in heavy drinkers. For A1298C polymorphism, CC alleles presented a possible preventive role for oral cancer. Collectively, results suggest that MTHFR 677TT polymorphism might be a low-penetrant risk factor for oral carcinoma only in heavy drinkers. Conversely, 1298CC alleles might play a preventive role for oral cancer." @default.
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• W2161405511 date "2012-04-26" @default.
• W2161405511 modified "2023-10-03" @default.
• W2161405511 title "Polymorphisms of MTHFR C677T and A1298C Association With Oral Carcinoma Risk: A Meta-Analysis" @default.
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• W2161405511 doi "https://doi.org/10.3109/07357907.2012.681820" @default.
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