Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161423503> ?p ?o ?g. }
- W2161423503 endingPage "163" @default.
- W2161423503 startingPage "156" @default.
- W2161423503 abstract "The present study aimed to determine different peripheral blood neutrophil functions in 18 morbidly obese subjects with body mass index (BMI) ranging between 35 and 69 kg/m(2) in parallel with age- and gender-matched lean controls. Peripheral blood neutrophil functions of obese subjects and matched lean controls were determined. Neutrophils of obese subjects showed significant elevation of the release of basal superoxides (P < 0.0001), formyl-methionyl-leucyl-phenylalanine (fMLP)-stimulated superoxides (P < 0.0001) and opsonized zymosan (OZ)-stimulated superoxides (P < 0.045) compared with lean controls. Interestingly, there were no differences in phorbol myristate acetate (PMA)-stimulated superoxide production by neutrophils of the obese subjects and controls. There was also a significant elevation of chemotactic (P < 0.0003) and random (P < 0.0001) migration of neutrophils from obese subjects compared with lean controls. Phagocytosis, CD11b surface expression and adherence of neutrophils from obese subjects were not significantly different from those of the lean controls. The elevated superoxide production and chemotactic activity, together with the normal phagocytosis and adherence, suggest that neutrophils from obese subjects are primed and have the capability to combat infections. However, neutrophils in the priming state may participate in the pathogenesis of obesity-related diseases." @default.
- W2161423503 created "2016-06-24" @default.
- W2161423503 creator A5005292042 @default.
- W2161423503 creator A5010917428 @default.
- W2161423503 creator A5030281337 @default.
- W2161423503 creator A5033898739 @default.
- W2161423503 creator A5074836733 @default.
- W2161423503 creator A5076227268 @default.
- W2161423503 creator A5080903939 @default.
- W2161423503 date "2015-05-13" @default.
- W2161423503 modified "2023-10-12" @default.
- W2161423503 title "Neutrophil functions in morbidly obese subjects" @default.
- W2161423503 cites W1608131589 @default.
- W2161423503 cites W1910361842 @default.
- W2161423503 cites W1915022071 @default.
- W2161423503 cites W1963984598 @default.
- W2161423503 cites W1970438085 @default.
- W2161423503 cites W1975537939 @default.
- W2161423503 cites W1979353742 @default.
- W2161423503 cites W1980942451 @default.
- W2161423503 cites W1990757970 @default.
- W2161423503 cites W1994907634 @default.
- W2161423503 cites W2005226810 @default.
- W2161423503 cites W2008869160 @default.
- W2161423503 cites W2009119724 @default.
- W2161423503 cites W2023754969 @default.
- W2161423503 cites W2026031033 @default.
- W2161423503 cites W2026841676 @default.
- W2161423503 cites W2039196730 @default.
- W2161423503 cites W2046497969 @default.
- W2161423503 cites W2053142936 @default.
- W2161423503 cites W2068565795 @default.
- W2161423503 cites W2070875481 @default.
- W2161423503 cites W2076633494 @default.
- W2161423503 cites W2077418603 @default.
- W2161423503 cites W2083260532 @default.
- W2161423503 cites W2085379324 @default.
- W2161423503 cites W2089892622 @default.
- W2161423503 cites W2090933153 @default.
- W2161423503 cites W2091272291 @default.
- W2161423503 cites W2092907781 @default.
- W2161423503 cites W2104987499 @default.
- W2161423503 cites W2105676684 @default.
- W2161423503 cites W2118193924 @default.
- W2161423503 cites W2119711390 @default.
- W2161423503 cites W2123192551 @default.
- W2161423503 cites W2124821727 @default.
- W2161423503 cites W2125220665 @default.
- W2161423503 cites W2125302795 @default.
- W2161423503 cites W2129468808 @default.
- W2161423503 cites W2131398405 @default.
- W2161423503 cites W2134133526 @default.
- W2161423503 cites W2136024338 @default.
- W2161423503 cites W2140114458 @default.
- W2161423503 cites W2146507509 @default.
- W2161423503 cites W2156274620 @default.
- W2161423503 cites W2156280702 @default.
- W2161423503 cites W2161310336 @default.
- W2161423503 cites W2165334726 @default.
- W2161423503 cites W2401754613 @default.
- W2161423503 cites W4238497443 @default.
- W2161423503 cites W4249727000 @default.
- W2161423503 cites W96832936 @default.
- W2161423503 doi "https://doi.org/10.1111/cei.12631" @default.
- W2161423503 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4469166" @default.
- W2161423503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25809538" @default.
- W2161423503 hasPublicationYear "2015" @default.
- W2161423503 type Work @default.
- W2161423503 sameAs 2161423503 @default.
- W2161423503 citedByCount "63" @default.
- W2161423503 countsByYear W21614235032015 @default.
- W2161423503 countsByYear W21614235032016 @default.
- W2161423503 countsByYear W21614235032017 @default.
- W2161423503 countsByYear W21614235032018 @default.
- W2161423503 countsByYear W21614235032019 @default.
- W2161423503 countsByYear W21614235032020 @default.
- W2161423503 countsByYear W21614235032021 @default.
- W2161423503 countsByYear W21614235032022 @default.
- W2161423503 countsByYear W21614235032023 @default.
- W2161423503 crossrefType "journal-article" @default.
- W2161423503 hasAuthorship W2161423503A5005292042 @default.
- W2161423503 hasAuthorship W2161423503A5010917428 @default.
- W2161423503 hasAuthorship W2161423503A5030281337 @default.
- W2161423503 hasAuthorship W2161423503A5033898739 @default.
- W2161423503 hasAuthorship W2161423503A5074836733 @default.
- W2161423503 hasAuthorship W2161423503A5076227268 @default.
- W2161423503 hasAuthorship W2161423503A5080903939 @default.
- W2161423503 hasBestOaLocation W21614235031 @default.
- W2161423503 hasConcept C126322002 @default.
- W2161423503 hasConcept C134018914 @default.
- W2161423503 hasConcept C160448771 @default.
- W2161423503 hasConcept C181199279 @default.
- W2161423503 hasConcept C198677920 @default.
- W2161423503 hasConcept C202751555 @default.
- W2161423503 hasConcept C203014093 @default.
- W2161423503 hasConcept C2776914184 @default.
- W2161423503 hasConcept C2778024521 @default.
- W2161423503 hasConcept C2778870864 @default.