FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161485774> ?p ?o ?g. }

• W2161485774 endingPage "1103" @default.
• W2161485774 startingPage "1098" @default.
• W2161485774 abstract "ABSTRACT Previous studies have suggested that currently available brucellosis vaccines induce poor or no protection in elk ( Cervus elaphus nelsoni ). In this study, we characterized the immunologic responses of elk after initial or booster vaccination with Brucella abortus strains RB51 (SRB51) and 19 (S19). Elk were vaccinated with saline or 10 10 CFU of SRB51 or S19 ( n = seven animals/treatment) and booster vaccinated with a similar dosage of the autologous vaccine at 65 weeks. Compared to nonvaccinates, elk vaccinated with SRB51 or S19 had greater ( P < 0.05) antibody responses to SRB51 or S19 after initial vaccination and after booster vaccination. Compared to nonvaccinated elk, greater ( P < 0.05) proliferative responses to autologous antigen after initial vaccination occurred at only a few sample times in SRB51 (6, 14, and 22 weeks) and S19 (22 weeks) treatment groups. In general, proliferative responses of vaccinates to nonautologous antigens did not differ ( P > 0.05) from the responses of nonvaccinated elk. Gamma interferon production in response to autologous or nonautologous Brucella antigens did not differ ( P > 0.05) between controls and vaccinates after booster vaccination. Flow cytometric techniques suggested that proliferation occurred more frequently in immunoglobulin M-positive cells, with differences between vaccination and control treatments in CD4 + and CD8 + subset proliferation detected only at 22 weeks after initial vaccination. After booster vaccination, one technique ([ 3 H]thymidine incorporation) suggested that proliferative responses to SRB51 antigen, but not S19 antigen, were greater ( P < 0.05) in vaccinates compared to the responses of nonvaccinates. However, in general, flow cytometric and other techniques failed to detect significant anamnestic responses to autologous or nonautologous Brucella antigens in S19 or SRB51 vaccinates after booster vaccination. Although some cellular immune responses were detected after initial or booster vaccination of elk with SRB51 or S19, our data suggest that responses tend to be transient and much less robust than previously reported in SRB51-vaccinated cattle ( Bos taurus ) or bison ( Bison bison ). These data may explain why the vaccination of elk with S19 and SRB51 induces poor protection against brucellosis." @default.
• W2161485774 created "2016-06-24" @default.
• W2161485774 creator A5007656234 @default.
• W2161485774 creator A5044437178 @default.
• W2161485774 creator A5060948358 @default.
• W2161485774 creator A5076034149 @default.
• W2161485774 creator A5083062182 @default.
• W2161485774 creator A5086924383 @default.
• W2161485774 date "2006-10-01" @default.
• W2161485774 modified "2023-10-06" @default.
• W2161485774 title "Immune Responses of Elk to Initial and Booster Vaccinations with <i>Brucella abortus</i> Strain RB51 or 19" @default.
• W2161485774 cites W1537978980 @default.
• W2161485774 cites W1851850927 @default.
• W2161485774 cites W1879557091 @default.
• W2161485774 cites W1919924159 @default.
• W2161485774 cites W1949297792 @default.
• W2161485774 cites W1974214703 @default.
• W2161485774 cites W1980333723 @default.
• W2161485774 cites W1991343021 @default.
• W2161485774 cites W2002024993 @default.
• W2161485774 cites W2013845301 @default.
• W2161485774 cites W2027283582 @default.
• W2161485774 cites W2047451661 @default.
• W2161485774 cites W2069657417 @default.
• W2161485774 cites W2073561976 @default.
• W2161485774 cites W2090574566 @default.
• W2161485774 cites W2108540658 @default.
• W2161485774 cites W2119985262 @default.
• W2161485774 cites W2120345995 @default.
• W2161485774 cites W2125042173 @default.
• W2161485774 cites W2128874472 @default.
• W2161485774 cites W2131633462 @default.
• W2161485774 cites W2151419780 @default.
• W2161485774 cites W2292086893 @default.
• W2161485774 cites W47302122 @default.
• W2161485774 doi "https://doi.org/10.1128/cvi.00213-06" @default.
• W2161485774 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1595328" @default.
• W2161485774 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17028213" @default.
• W2161485774 hasPublicationYear "2006" @default.
• W2161485774 type Work @default.
• W2161485774 sameAs 2161485774 @default.
• W2161485774 citedByCount "26" @default.
• W2161485774 countsByYear W21614857742012 @default.
• W2161485774 countsByYear W21614857742013 @default.
• W2161485774 countsByYear W21614857742014 @default.
• W2161485774 countsByYear W21614857742015 @default.
• W2161485774 countsByYear W21614857742016 @default.
• W2161485774 countsByYear W21614857742017 @default.
• W2161485774 countsByYear W21614857742018 @default.
• W2161485774 countsByYear W21614857742019 @default.
• W2161485774 crossrefType "journal-article" @default.
• W2161485774 hasAuthorship W2161485774A5007656234 @default.
• W2161485774 hasAuthorship W2161485774A5044437178 @default.
• W2161485774 hasAuthorship W2161485774A5060948358 @default.
• W2161485774 hasAuthorship W2161485774A5076034149 @default.
• W2161485774 hasAuthorship W2161485774A5083062182 @default.
• W2161485774 hasAuthorship W2161485774A5086924383 @default.
• W2161485774 hasBestOaLocation W21614857742 @default.
• W2161485774 hasConcept C121332964 @default.
• W2161485774 hasConcept C12590561 @default.
• W2161485774 hasConcept C1276947 @default.
• W2161485774 hasConcept C147483822 @default.
• W2161485774 hasConcept C159047783 @default.
• W2161485774 hasConcept C203014093 @default.
• W2161485774 hasConcept C203165030 @default.
• W2161485774 hasConcept C22070199 @default.
• W2161485774 hasConcept C2780801004 @default.
• W2161485774 hasConcept C2781429187 @default.
• W2161485774 hasConcept C71924100 @default.
• W2161485774 hasConcept C86803240 @default.
• W2161485774 hasConcept C8891405 @default.
• W2161485774 hasConceptScore W2161485774C121332964 @default.
• W2161485774 hasConceptScore W2161485774C12590561 @default.
• W2161485774 hasConceptScore W2161485774C1276947 @default.
• W2161485774 hasConceptScore W2161485774C147483822 @default.
• W2161485774 hasConceptScore W2161485774C159047783 @default.
• W2161485774 hasConceptScore W2161485774C203014093 @default.
• W2161485774 hasConceptScore W2161485774C203165030 @default.
• W2161485774 hasConceptScore W2161485774C22070199 @default.
• W2161485774 hasConceptScore W2161485774C2780801004 @default.
• W2161485774 hasConceptScore W2161485774C2781429187 @default.
• W2161485774 hasConceptScore W2161485774C71924100 @default.
• W2161485774 hasConceptScore W2161485774C86803240 @default.
• W2161485774 hasConceptScore W2161485774C8891405 @default.
• W2161485774 hasIssue "10" @default.
• W2161485774 hasLocation W21614857741 @default.
• W2161485774 hasLocation W21614857742 @default.
• W2161485774 hasLocation W21614857743 @default.
• W2161485774 hasLocation W21614857744 @default.
• W2161485774 hasOpenAccess W2161485774 @default.
• W2161485774 hasPrimaryLocation W21614857741 @default.
• W2161485774 hasRelatedWork W2324037830 @default.
• W2161485774 hasRelatedWork W2385876451 @default.
• W2161485774 hasRelatedWork W3201177512 @default.
• W2161485774 hasRelatedWork W4200574689 @default.
• W2161485774 hasRelatedWork W4207003944 @default.
• W2161485774 hasRelatedWork W4223961516 @default.
• W2161485774 hasRelatedWork W4283826450 @default.

• next