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- W2161497718 abstract "Human herpesvirus (HHV)-6 has been associated with the pathogenesis of multiple sclerosis (MS) on the basis of serologic, molecular, and histopathologic studies. This study sought to determine the distribution of HHV-6 in different MS body fluids, including serum, saliva, urine, and peripheral blood lymphocytes. The study results extend the observation of an increased frequency of HHV-6 DNA in serum of patients with MS to the unique detection of viral sequences in urine of a subset of patients with MS. Moreover, the HHV-6 identified in these cell-free compartments was predominantly the HHV-6A variant, which has been reported to be neurotropic. These results support the hypothesis that HHV-6 may contribute to the MS disease process." @default.
- W2161497718 created "2016-06-24" @default.
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- W2161497718 date "2000-11-01" @default.
- W2161497718 modified "2023-10-01" @default.
- W2161497718 title "Tissue Distribution and Variant Characterization of Human Herpesvirus (HHV)–6: Increased Prevalence of HHV‐6A in Patients with Multiple Sclerosis" @default.
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- W2161497718 doi "https://doi.org/10.1086/315893" @default.
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