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- W2161623204 abstract "Serum-immunoglobulin measurements in 11,000 hospital patients disclosed 24 propositi and 7 out of 15 of their relatives with idiopathic isolated γA deficiency. A review of these patients and published reports of other patients revealed that: (1) isolated γA deficiency has a prevalence of 1 in 500 and can be associated with ataxia telangiectasia; and (2) 69 of 75 patients had symptoms of recurrent sinopulmonary infection, or malabsorption, or thrombocytopenia, hypersplenism, and autoimmune syndromes. Evidence of defective humoral immunity with overcompensation of cellular immunity supports the hypothesis that immune imbalance can account for the symptomatology." @default.
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- W2161623204 date "1968-01-01" @default.
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- W2161623204 title "IMMUNE IMBALANCE IN DYSGAMMAGLOBULINÆEMIA TYPE IV" @default.
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- W2161623204 doi "https://doi.org/10.1016/s0140-6736(68)92721-9" @default.
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