FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2161721026> ?p ?o ?g. }

• W2161721026 endingPage "802" @default.
• W2161721026 startingPage "797" @default.
• W2161721026 abstract "Background Data regarding the treatment of nonsexually acquired genital ulceration (NSAGU) are limited. Objective We sought to provide evidence for the safety and efficacy of topical and systemic corticosteroids followed by doxycycline prophylaxis for acute and recurrent NSAGU. Methods A retrospective chart review was conducted of patients with NSAGU treated in a private dermogynecology practice. Results A total of 26 girls and women with NSAGU were identified and divided into 2 groups: group A = 17 patients with moderate to severe ulceration treated in the acute stage with oral corticosteroid; and group B = 9 patients with mild ulceration treated in the acute stage with topical corticosteroid. Patients in group A, with a mean age of 27.9 years (range, 11-62 years), were treated with oral prednisolone commencing with 15 to 50 mg per day depending on severity. Sixteen (94%) achieved rapid pain relief and complete healing of ulcers within 16 days. Eight (47%) commenced doxycycline prophylaxis. Women in group B, with a mean age of 42.5 years (range, 26-67 years) were treated with topical corticosteroids. Eight (89%) had a history of recurrent ulcers and 6 (66%) commenced doxycycline prophylaxis. Of all 14 patients on doxycycline prophylaxis, none reported any recurrences during a mean follow-up of 18.3 months. There were no adverse effects caused by prednisolone. One patient experienced mild photosensitivity from doxycycline but continued to take it. Limitations This was a retrospective case series from a single private practice–based population. Conclusion Topical or oral corticosteroids followed by prophylactic doxycycline can be effective in rapidly resolving acute flareups and preventing recurrences of NSAGU. All patients responded to therapy without treatment-limiting side effects. Data regarding the treatment of nonsexually acquired genital ulceration (NSAGU) are limited. We sought to provide evidence for the safety and efficacy of topical and systemic corticosteroids followed by doxycycline prophylaxis for acute and recurrent NSAGU. A retrospective chart review was conducted of patients with NSAGU treated in a private dermogynecology practice. A total of 26 girls and women with NSAGU were identified and divided into 2 groups: group A = 17 patients with moderate to severe ulceration treated in the acute stage with oral corticosteroid; and group B = 9 patients with mild ulceration treated in the acute stage with topical corticosteroid. Patients in group A, with a mean age of 27.9 years (range, 11-62 years), were treated with oral prednisolone commencing with 15 to 50 mg per day depending on severity. Sixteen (94%) achieved rapid pain relief and complete healing of ulcers within 16 days. Eight (47%) commenced doxycycline prophylaxis. Women in group B, with a mean age of 42.5 years (range, 26-67 years) were treated with topical corticosteroids. Eight (89%) had a history of recurrent ulcers and 6 (66%) commenced doxycycline prophylaxis. Of all 14 patients on doxycycline prophylaxis, none reported any recurrences during a mean follow-up of 18.3 months. There were no adverse effects caused by prednisolone. One patient experienced mild photosensitivity from doxycycline but continued to take it. This was a retrospective case series from a single private practice–based population. Topical or oral corticosteroids followed by prophylactic doxycycline can be effective in rapidly resolving acute flareups and preventing recurrences of NSAGU. All patients responded to therapy without treatment-limiting side effects." @default.
• W2161721026 created "2016-06-24" @default.
• W2161721026 creator A5022675153 @default.
• W2161721026 creator A5033591916 @default.
• W2161721026 creator A5044429182 @default.
• W2161721026 date "2013-05-01" @default.
• W2161721026 modified "2023-10-03" @default.
• W2161721026 title "Management of nonsexually acquired genital ulceration using oral and topical corticosteroids followed by doxycycline prophylaxis" @default.
• W2161721026 cites W1494954116 @default.
• W2161721026 cites W1521038532 @default.
• W2161721026 cites W1879089629 @default.
• W2161721026 cites W1981216245 @default.
• W2161721026 cites W2024192096 @default.
• W2161721026 cites W2030890933 @default.
• W2161721026 cites W2036666544 @default.
• W2161721026 cites W2052157191 @default.
• W2161721026 cites W2086499646 @default.
• W2161721026 cites W2095737608 @default.
• W2161721026 cites W2105164827 @default.
• W2161721026 cites W2108151611 @default.
• W2161721026 cites W2128090527 @default.
• W2161721026 cites W2130460164 @default.
• W2161721026 cites W2135229583 @default.
• W2161721026 cites W2158806397 @default.
• W2161721026 cites W2166946754 @default.
• W2161721026 cites W2168273486 @default.
• W2161721026 doi "https://doi.org/10.1016/j.jaad.2012.10.014" @default.
• W2161721026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23182067" @default.
• W2161721026 hasPublicationYear "2013" @default.
• W2161721026 type Work @default.
• W2161721026 sameAs 2161721026 @default.
• W2161721026 citedByCount "28" @default.
• W2161721026 countsByYear W21617210262013 @default.
• W2161721026 countsByYear W21617210262014 @default.
• W2161721026 countsByYear W21617210262015 @default.
• W2161721026 countsByYear W21617210262016 @default.
• W2161721026 countsByYear W21617210262017 @default.
• W2161721026 countsByYear W21617210262018 @default.
• W2161721026 countsByYear W21617210262019 @default.
• W2161721026 countsByYear W21617210262020 @default.
• W2161721026 countsByYear W21617210262021 @default.
• W2161721026 countsByYear W21617210262022 @default.
• W2161721026 countsByYear W21617210262023 @default.
• W2161721026 crossrefType "journal-article" @default.
• W2161721026 hasAuthorship W2161721026A5022675153 @default.
• W2161721026 hasAuthorship W2161721026A5033591916 @default.
• W2161721026 hasAuthorship W2161721026A5044429182 @default.
• W2161721026 hasConcept C126322002 @default.
• W2161721026 hasConcept C141071460 @default.
• W2161721026 hasConcept C16005928 @default.
• W2161721026 hasConcept C167135981 @default.
• W2161721026 hasConcept C197934379 @default.
• W2161721026 hasConcept C2776715498 @default.
• W2161721026 hasConcept C2776804153 @default.
• W2161721026 hasConcept C2777179404 @default.
• W2161721026 hasConcept C501593827 @default.
• W2161721026 hasConcept C71924100 @default.
• W2161721026 hasConcept C86803240 @default.
• W2161721026 hasConcept C89423630 @default.
• W2161721026 hasConceptScore W2161721026C126322002 @default.
• W2161721026 hasConceptScore W2161721026C141071460 @default.
• W2161721026 hasConceptScore W2161721026C16005928 @default.
• W2161721026 hasConceptScore W2161721026C167135981 @default.
• W2161721026 hasConceptScore W2161721026C197934379 @default.
• W2161721026 hasConceptScore W2161721026C2776715498 @default.
• W2161721026 hasConceptScore W2161721026C2776804153 @default.
• W2161721026 hasConceptScore W2161721026C2777179404 @default.
• W2161721026 hasConceptScore W2161721026C501593827 @default.
• W2161721026 hasConceptScore W2161721026C71924100 @default.
• W2161721026 hasConceptScore W2161721026C86803240 @default.
• W2161721026 hasConceptScore W2161721026C89423630 @default.
• W2161721026 hasIssue "5" @default.
• W2161721026 hasLocation W21617210261 @default.
• W2161721026 hasLocation W21617210262 @default.
• W2161721026 hasOpenAccess W2161721026 @default.
• W2161721026 hasPrimaryLocation W21617210261 @default.
• W2161721026 hasRelatedWork W1971984977 @default.
• W2161721026 hasRelatedWork W1993512576 @default.
• W2161721026 hasRelatedWork W2028736220 @default.
• W2161721026 hasRelatedWork W2047967234 @default.
• W2161721026 hasRelatedWork W2144529889 @default.
• W2161721026 hasRelatedWork W2439875401 @default.
• W2161721026 hasRelatedWork W2472001820 @default.
• W2161721026 hasRelatedWork W2621101998 @default.
• W2161721026 hasRelatedWork W3113146271 @default.
• W2161721026 hasRelatedWork W4239374029 @default.
• W2161721026 hasVolume "68" @default.
• W2161721026 isParatext "false" @default.
• W2161721026 isRetracted "false" @default.
• W2161721026 magId "2161721026" @default.
• W2161721026 workType "article" @default.