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- W2161922768 abstract "This thesis study focuses on synthesizing and characterizing gold-magnetite optically active magnetic nanoparticle and its conjugation with biomolecules for biomedical applications, especially magnetic fluid hyperthermia treatment for cancerous tissue. Gold nanoparticles have already displayed their potential in the biomedical field. They exhibit excellent optical properties and possess strong surface chemistry which renders them suitable for various biomolecule attachments. Studies have showed gold nanoparticles to be a perfect biocompatible vector. However, clinical trials for gold mediated drug delivery and treatment studied in rat models identified some problems. Of these problems, the low retention time in bloodstream and inability to maneuver externally has been the consequential. To further enhance their potential applications and overcome the problems faced in using gold nanoparticles alone, many researchers have synthesized multifunctional magnetic materials with gold at one terminal. Magnetite, among the investigated magnetic materials is a promising and reliable candidate because of its high magnetic saturation moment and low toxicity. This thesis showcases a simple and facile one pot synthesis of gold-magnetite nanoparticles with an average particle size of 80 nm through hot injection method. The as-synthesized nanoparticles were characterized by XRD, TEM, Mӧssbauer spectroscopy, SQUID and MTS toxicity studies. The superparamagnetism of the as-synthesized nanoparticles has an interestingly high saturation magnetization moment and low toxicity than the literature values reported earlier. L-cysteine and (-)-EGCG (epigallacatechin-3-gallate) were attached to this multifunctional nanoparticles through the gold terminal and characterized to show the particles applicability through Raman, FTIR and UV-Vis spectroscopy." @default.
- W2161922768 created "2016-06-24" @default.
- W2161922768 creator A5041645318 @default.
- W2161922768 date "2014-01-01" @default.
- W2161922768 modified "2023-09-27" @default.
- W2161922768 title "Gold-magnetite nanoparticle-biomolecule conjugates: Synthesis, properties and toxicity studies" @default.
- W2161922768 cites W1510613202 @default.
- W2161922768 cites W1553330897 @default.
- W2161922768 cites W1573111014 @default.
- W2161922768 cites W1656896514 @default.
- W2161922768 cites W1670905992 @default.
- W2161922768 cites W1955897922 @default.
- W2161922768 cites W1963552788 @default.
- W2161922768 cites W1963807187 @default.
- W2161922768 cites W1965665097 @default.
- W2161922768 cites W1968044889 @default.
- W2161922768 cites W1973271578 @default.
- W2161922768 cites W1976178939 @default.
- W2161922768 cites W1978648897 @default.
- W2161922768 cites W1979232921 @default.
- W2161922768 cites W1980515448 @default.
- W2161922768 cites W1987974230 @default.
- W2161922768 cites W1991696319 @default.
- W2161922768 cites W1992364959 @default.
- W2161922768 cites W1993504067 @default.
- W2161922768 cites W1995928849 @default.
- W2161922768 cites W1996139192 @default.
- W2161922768 cites W2001719483 @default.
- W2161922768 cites W2003336829 @default.
- W2161922768 cites W2012313054 @default.
- W2161922768 cites W2012892192 @default.
- W2161922768 cites W2014777534 @default.
- W2161922768 cites W2015856769 @default.
- W2161922768 cites W2017341614 @default.
- W2161922768 cites W2020451212 @default.
- W2161922768 cites W2020696334 @default.
- W2161922768 cites W2027231021 @default.
- W2161922768 cites W2028085557 @default.
- W2161922768 cites W2030107850 @default.
- W2161922768 cites W2031846624 @default.
- W2161922768 cites W2032186406 @default.
- W2161922768 cites W2033005915 @default.
- W2161922768 cites W2033096857 @default.
- W2161922768 cites W2034105791 @default.
- W2161922768 cites W2035534563 @default.
- W2161922768 cites W2037226786 @default.
- W2161922768 cites W2042394648 @default.
- W2161922768 cites W2042758892 @default.
- W2161922768 cites W2043646007 @default.
- W2161922768 cites W2044440155 @default.
- W2161922768 cites W2044980243 @default.
- W2161922768 cites W2045276693 @default.
- W2161922768 cites W2045363998 @default.
- W2161922768 cites W2047736192 @default.
- W2161922768 cites W2049321277 @default.
- W2161922768 cites W2052051931 @default.
- W2161922768 cites W2052566608 @default.
- W2161922768 cites W2053037334 @default.
- W2161922768 cites W2054603000 @default.
- W2161922768 cites W2055222641 @default.
- W2161922768 cites W2055944585 @default.
- W2161922768 cites W2056376041 @default.
- W2161922768 cites W2060429741 @default.
- W2161922768 cites W2062897862 @default.
- W2161922768 cites W2065153300 @default.
- W2161922768 cites W2071659125 @default.
- W2161922768 cites W2073126015 @default.
- W2161922768 cites W2077140060 @default.
- W2161922768 cites W2077228161 @default.
- W2161922768 cites W2081130717 @default.
- W2161922768 cites W2081508622 @default.
- W2161922768 cites W2083738921 @default.
- W2161922768 cites W2083876006 @default.
- W2161922768 cites W2084025743 @default.
- W2161922768 cites W2084871302 @default.
- W2161922768 cites W2094907332 @default.
- W2161922768 cites W2095007454 @default.
- W2161922768 cites W2095708811 @default.
- W2161922768 cites W2096625313 @default.
- W2161922768 cites W2102492267 @default.
- W2161922768 cites W2109610797 @default.
- W2161922768 cites W2112165279 @default.
- W2161922768 cites W2115029038 @default.
- W2161922768 cites W2117053902 @default.
- W2161922768 cites W2121830147 @default.
- W2161922768 cites W2123605247 @default.
- W2161922768 cites W2123976897 @default.
- W2161922768 cites W2126346850 @default.
- W2161922768 cites W2126597927 @default.
- W2161922768 cites W2131430454 @default.
- W2161922768 cites W2131848081 @default.
- W2161922768 cites W2132729019 @default.
- W2161922768 cites W2137374477 @default.
- W2161922768 cites W2140181820 @default.
- W2161922768 cites W2140294035 @default.
- W2161922768 cites W2144466990 @default.
- W2161922768 cites W2144949343 @default.
- W2161922768 cites W2145238798 @default.
- W2161922768 cites W2146002957 @default.
- W2161922768 cites W2148936002 @default.