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• W2161922804 abstract "Octapeptide R2 (KVLDGQDP), which has anti-transglutaminas (TGase) activity, decreases inflammation in allergic conjunctivitis model in guinea pigs. The authors examined the effect of R2 on lipopolysaccharide (LPS)-induced lung injury in BALB/c mice. R2 inhalation significantly decreased neutrophil count and cytokine mRNA expression in the lungs of LPS (25 mg/kg)-treated mice (P < .05). It also showed a tendency for decreased tumor necrosis factor (TNF)-α–immunoreactive protein in lung homogenates and significantly decreased TNF-α–immunoreactive protein in the serum of LPS-injected mice (P < .05). These results indicate that TGase may be a new therapeutic target in LPS-induced lung inflammation." @default.
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• W2161922804 date "2006-01-01" @default.
• W2161922804 modified "2023-09-26" @default.
• W2161922804 title "A PEPTIDE WITH ANTI-TRANSGLUTAMINASE ACTIVITY DECREASES LIPOPOLYSACCHARIDE-INDUCED LUNG INFLAMMATION IN MICE" @default.
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• W2161922804 doi "https://doi.org/10.1080/01902140600691514" @default.
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